Pioneer of infertility treatment. Covering the needs of infertility from various tests 
to IVF/ICSI’s Advanced Reproductive Technologies.

〔Sumiyoshi&Ginza〕Endometrial Receptivity Analysis(ERA) Guidance

■ What is ERA(Endometrial Receptivity Analysis)?

ERA is a test to determine at what point in time the endometrium is most receptive for a successful transplant.
It checks the DNA levels, and whether or not the endometrium is receptive to implantation, on the day of the transfer, when transferring the frozen-thawed blastocyst. In cases of implantation failure, even when the endometrium is in a good physical condition of being able to receive an implant, there are cases when the DNA level is not sufficient and in such situations it will take even more time to reach the time period where a successful implantation may be obtained.
❈During the test cycle, there will be no transfers.  We will only do the test.

 

About ERA

 

1) Test Method

Flow of ERA Test

1st Cycle

We will use the same medicine that is used in the hormone support cycle timed just like a thawed embryo transfer.

 

1. Thawed Embryo Transfer Cases
  1. (1) Estrogen will be taken from Day 2 of menstruation.
  2. (2) We will check the thickness of the endometrium around Day 12 of menstruation (those far away, may be omitted).
  3. (3) Progesterone use will begin and on Day 5 of use endometrial tissue sample will be taken and sent away for the test.

 

2. Natural Cycle Cases

The test will be done on 5th day after ovulation is confirmed.

 

2-3 weeks are needed to get the test results.

 

Test Results  
Receptive The endometrium is in a condition where implantation is possible.  The testing finishes here.  On the next cycle by means of the same method, progesterone is used and on Day 5 the blastocyst will be transferred.
Non receotive The endometrium is not receptive for implantation. Move on to 2nd Cycle testing.

 

2nd Cycle

The 2nd Cycle Testing will be done in the same manner as in the 1st Cycle.

The taking of the endometrial tissue in the hormone support cycle will be done between Day 3 or Day 4 after the start of progesterone, or on Day 7(or both). In the natural cycle, the test will be done between 3rd day or 4th day after ovulation has been confirmed, or on 7th day(or both).

 

 


2) Regarding Endometrial Tissue Retrieval

Regarding Endometrial Tissue Retrieval

 

The procedure will take about 5 minutes. In most cases it will be done without anesthesia. It is not necessary to stop eating before this procedure.
However, because there may be pain associated with the insertion of the curette, the procedure can be done under a local anesthetic.


There is a pain, but the kind of pain expected during menstruation and will only be for an instant. For patients who have low tolerance to pain, the dispensing of pain killers will be considered by patient request through consultation. Additionally it is very rare, but a general anesthesia (intravenous) is sometimes requested. It is possible to handle this request, but because fasting and pretreatment is necessary, please let us know beforehand if you strongly want this treatment.
A separate fee is needed for anesthesia and pretreatment.


On the day of the procedure a shower is permissible(taking bath is restricted). Additionally, PLEASE DO NOT engage in sexual activities on the day of procedure.

 

 


3) Endometrial Receptivity Analysis(ERA) Costs

  Patients having IVF done
at our clinic
Patients, other than left
1st Cycle Test Cost ¥165,000 ¥265,000
2nd Cycle Test Cost ¥147,000 ¥247,000
  • Displayed costs are all without tax.
  • Costs are subject to change without notice.
  • Costs of medicine, ultrasound, other tests are done at a separate cost.

 

4) Endometrial Receptivity Analysis(ERA) Test Related Page

 

 

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Oak Medical Group has been from the time we opened, supporting the many issues of women's health, building performance and trust, and not only here in Osaka, but centering in Kansai we are receiving patients from across Japan.
Especially with our infertility treatment, we are widely covering the various tests to IVF/ICSI's Advanced Reproductive Technologies.  Depending on the cause of the infertility, we are handling the treatment of each patient one by one.  If you have some concerns, please don't hesitate to consult with us.