{"id":1490,"date":"2024-10-08T19:47:28","date_gmt":"2024-10-08T10:47:28","guid":{"rendered":"https:\/\/www.oakclinic-group.com\/wp\/nmn_drip\/"},"modified":"2025-02-12T09:19:46","modified_gmt":"2025-02-12T00:19:46","slug":"nmn_drip","status":"publish","type":"page","link":"https:\/\/www.oakclinic-group.com\/zh\/infertility\/nmn_drip\/","title":{"rendered":"NMN\u6ef4\u6ce8\u7597\u6cd5"},"content":{"rendered":"<div class=\"section-dept__container\">\r\n<div class=\"section-dept__first_content\">\r\n<section class=\"section-dept__content01\">\r\n<h1 class=\"section-dept__content01_title\">\r\n     NMN\u6ef4\u6ce8\u7597\u6cd5\r\n     <span style=\"font-size:0.85em;\">\r\n      \u03b2-Nicotinamide Mononucleotide\r\n     <\/span>\r\n<\/h1>\r\n<!-- \u5404\u30af\u30ea\u30cb\u30c3\u30af -->\r\n<div class=\"float_right pt10\">\r\n<p>\r\n<span class=\"text_frame2\">\r\n<a href=\"https:\/\/www.oakclinic-group.com\/zh\/sumiyoshi\/\">\r\n        \u4f4f\u5409\r\n       <\/a>\r\n<\/span>\r\n<span class=\"text_frame2\">\r\n<a href=\"https:\/\/www.oakclinic-group.com\/zh\/umeda_ladys\/\">\r\n        \u6885\u7530\r\n       <\/a>\r\n<\/span>\r\n<span class=\"text_frame2\">\r\n<a href=\"https:\/\/www.oakclinic-group.com\/zh\/ginza_ladys\/\">\r\n        \u94f6\u5ea7\r\n       <\/a>\r\n<\/span>\r\n<\/p>\r\n<\/div>\r\n<p style=\"clear: both;\">\r\n<\/p>\r\n<!-- \u5404\u30af\u30ea\u30cb\u30c3\u30af \u3053\u3053\u307e\u3067 -->\r\n<div class=\"section-dept__content01_text mt-50\">\r\n<div class=\"section-dept__content02_text\">\r\n<div class=\"ivf_icsi_cap\">\r\n<div class=\"ivf_text02 mt20\">\r\n<p>\r\n         NMN\u6ef4\u6ce8\u7597\u6cd5\uff08\u03b2-Nicotinamide Mononucleotide\uff09\u662f\u54c8\u4f5b\u5927\u5b66\u533b\u5b66\u90e8\u7814\u7a76\u4e2d\u53d1\u73b0\u7684\u5177\u6709\u5e74\u8f7b\u5316\u6548\u679c\u7684\u4e0b\u4e00\u4ee3\u6297\u8870\u8001\u7597\u6cd5\u3002\r\n        <\/p>\r\n<ul class=\"list_type1 bold\">\r\n<li>\r\n          \u6d3b\u5316sirtuin\uff08\u957f\u5bff\uff09\u57fa\u56e0\uff0c\u7115\u53d1\u9752\u6625\u6d3b\u529b\r\n         <\/li>\r\n<li>\r\n          \u4f53\u8102\u80aa\u7387\u51cf\u5c11\uff0c\u808c\u8089\u7387\u589e\u52a0\r\n         <\/li>\r\n<li>\r\n          \u4f53\u529b\u6062\u590d\r\n         <\/li>\r\n<li>\r\n          \u80fd\u591f\u6df1\u5ea6\u7761\u7720\r\n         <\/li>\r\n<li>\r\n          \u96cc\u6fc0\u7d20\u589e\u52a0\r\n         <\/li>\r\n<li>\r\n          \u8fd0\u52a8\u65f6\u547c\u5438\u53d8\u5f97\u8f7b\u677e\r\n         <\/li>\r\n<li>\r\n          \u808c\u80a4\u7684\u7ec6\u7eb9\u3001\u5f39\u6027\u3001\u7f8e\u767d\u90fd\u6709\u6240\u63d0\u5347\r\n         <\/li>\r\n<li>\r\n          \u6fc0\u6d3b\u7ebf\u7c92\u4f53\r\n         <\/li>\r\n<li>\r\n          \u5934\u8111\u66f4\u4e3a\u6e05\u6670\r\n         <\/li>\r\n<li>\r\n          \u601d\u8003\u548c\u96c6\u4e2d\u80fd\u529b\u589e\u5f3a\r\n         <\/li>\r\n<li>\r\n          \u4ee3\u8c22\u63d0\u9ad8\r\n         <\/li>\r\n<\/ul>\r\n<\/div>\r\n<figure class=\"ivf00 mt20\">\r\n<img decoding=\"async\" alt=\"NMN\u6ef4\u6ce8\u7597\u6cd5\u5f62\u8c61\" src=\"https:\/\/www.oakclinic-group.com\/wp\/wp-content\/themes\/oak-clinic\/zh\/assets\/images\/infertility\/nmn_image.png\"\/>\r\n<\/figure>\r\n<div class=\"ivf pb10\">\r\n<p class=\"headline\">\r\n<a href=\"https:\/\/www.oakclinic-group.com\/zh\/infertility\/#activation\">\r\n          \u901a\u8fc7NMN\u6ef4\u6ce8\u7597\u6cd5\u6d3b\u5316sirtuin\uff08\u957f\u5bff\uff09\u57fa\u56e0\u662f\u4ec0\u4e48\r\n          <img decoding=\"async\" alt=\"\u4e38\" src=\"https:\/\/www.oakclinic-group.com\/wp\/wp-content\/themes\/oak-clinic\/assets\/images\/funin\/headline_circle_btn.png\"\/>\r\n<\/a>\r\n<\/p>\r\n<\/div>\r\n<div class=\"ivf pb10\">\r\n<p class=\"headline\">\r\n<a href=\"https:\/\/www.oakclinic-group.com\/zh\/infertility\/#about_nmn\">\r\n          \u4ec0\u4e48\u662fNMN\r\n          <img decoding=\"async\" alt=\"\u4e38\" src=\"https:\/\/www.oakclinic-group.com\/wp\/wp-content\/themes\/oak-clinic\/assets\/images\/funin\/headline_circle_btn.png\"\/>\r\n<\/a>\r\n<\/p>\r\n<\/div>\r\n<div class=\"ivf pb10\">\r\n<p class=\"headline\">\r\n<a href=\"https:\/\/www.oakclinic-group.com\/zh\/infertility\/#disease\">\r\n          \u53ef\u671f\u5f85\u7684\u6cbb\u7597\u6548\u679c\u7684\u75be\u75c5\r\n          <img decoding=\"async\" alt=\"\u4e38\" src=\"https:\/\/www.oakclinic-group.com\/wp\/wp-content\/themes\/oak-clinic\/assets\/images\/funin\/headline_circle_btn.png\"\/>\r\n<\/a>\r\n<\/p>\r\n<\/div>\r\n<div class=\"ivf pb10\">\r\n<p class=\"headline\">\r\n<a href=\"https:\/\/www.oakclinic-group.com\/zh\/infertility\/#treatment\">\r\n          \u6cbb\u7597\u65b9\u6cd5\r\n          <img decoding=\"async\" alt=\"\u4e38\" src=\"https:\/\/www.oakclinic-group.com\/wp\/wp-content\/themes\/oak-clinic\/assets\/images\/funin\/headline_circle_btn.png\"\/>\r\n<\/a>\r\n<\/p>\r\n<\/div>\r\n<div class=\"ivf pb10\">\r\n<p class=\"headline\">\r\n<a href=\"https:\/\/www.oakclinic-group.com\/zh\/infertility\/#side_effects\">\r\n          NMN\u6ef4\u6ce8\u7597\u6cd5\u7684\u7981\u5fcc\u548c\u526f\u4f5c\u7528\r\n          <img decoding=\"async\" alt=\"\u4e38\" src=\"https:\/\/www.oakclinic-group.com\/wp\/wp-content\/themes\/oak-clinic\/assets\/images\/funin\/headline_circle_btn.png\"\/>\r\n<\/a>\r\n<\/p>\r\n<\/div>\r\n<div class=\"ivf pb10\">\r\n<p class=\"headline\">\r\n<a href=\"https:\/\/www.oakclinic-group.com\/zh\/infertility\/#nmn_fees\">\r\n          NMN\u6ef4\u6ce8\u7597\u6cd5\u7684\u8d39\u7528\r\n          <img decoding=\"async\" alt=\"\u4e38\" src=\"https:\/\/www.oakclinic-group.com\/wp\/wp-content\/themes\/oak-clinic\/assets\/images\/funin\/headline_circle_btn.png\"\/>\r\n<\/a>\r\n<\/p>\r\n<\/div>\r\n<div class=\"ivf pb10\">\r\n<p class=\"headline\">\r\n<a href=\"https:\/\/www.oakclinic-group.com\/zh\/infertility\/#quality\">\r\n          NMN\u539f\u6750\u6599\u7684\u8d28\u91cf\r\n          <img decoding=\"async\" alt=\"\u4e38\" src=\"https:\/\/www.oakclinic-group.com\/wp\/wp-content\/themes\/oak-clinic\/assets\/images\/funin\/headline_circle_btn.png\"\/>\r\n<\/a>\r\n<\/p>\r\n<\/div>\r\n<div class=\"ivf pb10\">\r\n<p class=\"headline\">\r\n<a href=\"https:\/\/www.oakclinic-group.com\/zh\/infertility\/#treatise\">\r\n          \u53c2\u8003\u6587\u732e\r\n          <img decoding=\"async\" alt=\"\u4e38\" src=\"https:\/\/www.oakclinic-group.com\/wp\/wp-content\/themes\/oak-clinic\/assets\/images\/funin\/headline_circle_btn.png\"\/>\r\n<\/a>\r\n<\/p>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<div id=\"activation\">\r\n<\/div>\r\n<h2 class=\"section-dept__content02_title\">\r\n     \u901a\u8fc7NMN\u6ef4\u6ce8\u7597\u6cd5\u5982\u4f55\u6fc0\u6d3bsirtuin\uff08\u957f\u5bff\uff09\u57fa\u56e0\r\n    <\/h2>\r\n<div class=\"section-dept__content02_text\">\r\n<p>\r\n      \u6bcf\u4e2a\u4eba\u90fd\u5e0c\u671b\u6c38\u8fdc\u5e74\u8f7b\u5065\u5eb7\u3002\r\n      <br\/>\r\n      \u4f46\u968f\u7740\u5e74\u9f84\u7684\u589e\u957f\uff0c\u76ae\u80a4\u548c\u4f53\u529b\u4e5f\u4f1a\u9010\u6e10\u8870\u9000\uff0c\u53d8\u5f97\u4e0e\u5e74\u9f84\u76f8\u79f0\u3002\r\n      <br\/>\r\n      \u90a3\u4e48\uff0c\u662f\u4ec0\u4e48\u6210\u4e3a\u4e86\u8001\u5316\u7684\u539f\u56e0\u5462\uff1f\u5b58\u5728\u4e0e\u4eba\u7c7b\u8001\u5316\u548c\u5bff\u547d\u6df1\u5ea6\u76f8\u5173\u7684\u57fa\u56e0\u3002\r\n      <br\/>\r\n      \u90a3\u5c31\u662f\u201csirtuin\u57fa\u56e0\uff08\u957f\u5bff\u57fa\u56e0\uff09\u201d\u3002\r\n      <br\/>\r\n      \u6fc0\u6d3b\u8fd9\u4e2a\u57fa\u56e0\u53ef\u4ee5\u6539\u5584\u76ae\u80a4\u7ec6\u80de\u3001\u4f53\u529b\u548c\u75b2\u52b3\u7b49\u8eab\u4f53\u529f\u80fd\uff0c\u5e76\u5e26\u6765\u5e74\u8f7b\u5316\u6548\u679c\u3002\r\n      <br\/>\r\n      NMN\u6ef4\u6ce8\u5c31\u662f\u4e3a\u4e86\u6fc0\u6d3b\u8fd9\u4e2asirtuin\u57fa\u56e0\uff0c\u8ba9\u60a8\u957f\u65f6\u95f4\u4fdd\u6301\u5e74\u8f7b\uff0c\u5e76\u8fc7\u4e0a\u5065\u5eb7\u7684\u751f\u6d3b\u3002\r\n     <\/p>\r\n<\/div>\r\n<div id=\"about_nmn\">\r\n<\/div>\r\n<h2 class=\"section-dept__content02_title\">\r\n     NMN\u662f\u4ec0\u4e48\r\n    <\/h2>\r\n<div class=\"section-dept__content02_text\">\r\n                              <p>\u6b63\u5f0f\u540d\u79f0\u4e3a\u300c\u70df\u9170\u80fa\u5355\u6838\u82f7\u9178\u300d\u3002<br>\r\n                                  NMN\u662f\u4e00\u79cd\u7c7b\u4f3c\u4e8e\u7ef4\u751f\u7d20\u7684\u7269\u8d28\uff0c\u8eab\u4f53\u5185\u90e8\u4f1a\u81ea\u7136\u4ea7\u751f\u3002<br>\r\n                                  \u4f46\u968f\u7740\u5e74\u9f84\u589e\u957f\uff0c\u8eab\u4f53\u5185\u7684\u4ea7\u91cf\u4f1a\u51cf\u5c11\u3002<br>\r\n                                  \u5f53\u4f53\u5185\u7684NMN\u51cf\u5c11\u65f6\uff0c\u8001\u5316\u5f00\u59cb\uff0c\u8eab\u4f53\u529f\u80fd\u548c\u8ba4\u77e5\u529f\u80fd\u7684\u8870\u8001\u4e5f\u968f\u4e4b\u52a0\u901f\u3002<br>\r\n                                  \u6444\u53d6\u8fd9\u79cdNMN\u53ef\u4ee5\u4f7f\u8eab\u4f53\u7684\u5916\u89c2\u548c\u529f\u80fd\u53d1\u751f\u5de8\u5927\u53d8\u5316\uff0c\u5982\u540c\u5012\u8f6c\u65f6\u95f4\u7684\u6307\u9488\u3002\u8fd9\u6837\u7684\u7814\u7a76\u9646\u7eed\u88ab\u516c\u5e03\uff0c\u5e76\u88ab\u5168\u4e16\u754c\u79f0\u4e3a\u201c\u8fd8\u539f\u9752\u6625\u7684\u836f\u7269\u201d\u3002<\/p>\r\n                              <p>\u987a\u4fbf\u8bf4\u4e00\u4e0b\uff0c\u5bcc\u542bNMN\u7684\u98df\u54c1\u6709\u6bdb\u8c46\u3001\u82b1\u6930\u83dc\u3001\u9ec4\u74dc\u7b49\uff0c\u4f46\u60f3\u901a\u8fc7\u82b1\u6930\u83dc\u6bcf\u5929\u6444\u53d6100mg\u7684NMN\uff0c\u5c31\u9700\u8981\u7ea640kg\uff08\u7ea62000\u675f\uff09\u3002<br>\r\n                                  \u901a\u8fc7\u70b9\u6ef4\uff0c\u53ef\u4ee5\u9ad8\u6548\u5730\u5c06NMN\u5f15\u5165\u4f53\u5185\u3002<!--\u54c8\u4f5b\u5927\u5b66\u533b\u5b66\u90e8\u7684David Sinclair\u6559\u6388\u66fe\u8fd9\u6837\u63cf\u8ff0NMN\uff1a--><\/p>\r\n\r\n                                <p class=\"mb30 mt100\">\u901a\u8fc7NMN\u53ef\u80fd\u6539\u5584\u5375\u5de2\u529f\u80fd\u3001\u5375\u5b50\u8d28\u91cf\u4ee5\u53ca\u7cbe\u5b50\u8d28\u91cf\u7684\u53ef\u80fd\u6027\u5df2\u88ab\u63d0\u51fa\u30021\uff092\uff093\uff094\uff095\uff09<\/p>\r\n                                <p class=\"text-indent: -1em;\r\n                            padding-left: 1em;\">\r\n                              <strong>\uff11\uff09Cell Prolif. 2022 Jul 10;55(11):e13303. doi: 10.1111\/cpr.13303<br>\r\n                              Administration of nicotinamide mononucleotide improves oocyte quality of obese mice<\/strong><br>\r\n                              Luyao Wang 1 2, Yurong Chen 1 2, Jiarui Wei 1 2, Fucheng Guo 1 2, Leyi Li 1 2, Zhen Han 1 2, Zhengzhu Wang 1 2, Haibo Zhu 3, Xiaoling Zhang 1 2, Ziyi Li 1 2, Xiangpeng Dai 1 2<br>\r\n                            <\/p>\r\n                            <!--<p>\r\n                              <strong>\uff12\uff092020 Aug 4;32(5):107987. doi: 10.1016\/j.celrep.2020.107987.<\/strong><br>\r\n                              Nicotinamide Mononucleotide Supplementation Reverses the Declining Quality of Maternally Aged Oocytes\r\n                              Yilong Miao 1, Zhaokang Cui 1, Qian Gao 2, Rong Rui 2, Bo Xiong 3\r\n                              Affiliations Expand<br>\r\n                            <br>\r\n                              Anim Biosci<br>\r\n                            <\/p>-->\r\n                            <p>\r\n                              <strong>\uff12\uff09 2020 Feb 11;30(6):1670-1681.e7. doi: 10.1016\/j.celrep.2020.01.058.<br>\r\n                              NAD+ Repletion Rescues Female Fertility during Reproductive Aging<\/strong><br>\r\n                              Michael J Bertoldo 1, Dave R Listijono 1, Wing-Hong Jonathan Ho 1, Angelique H Riepsamen 2, Dale M Goss 3, Dulama Richani 2, Xing L Jin 4, Saabah Mahbub 5, Jared M Campbell 5, Abbas Habibalahi 5, Wei-Guo Nicholas Loh 2, Neil A Youngson 3, Jayanthi Maniam 3, Ashley S A Wong 3, Kaisa Selesniemi 6, Sonia Bustamante 7, Catherine Li 3, Yiqing Zhao 2, Maria B Marinova 2, Lynn-Jee Kim 3, Laurin Lau 2, Rachael M Wu 8, A Stefanie Mikolaizak 9, Toshiyuki Araki 10, David G Le Couteur 11, Nigel Turner 3, Margaret J Morris 3, Kirsty A Walters 2, Ewa Goldys 5, Christopher O'Neill 4, Robert B Gilchrist 2, David A Sinclair 12, Hayden A Homer 13, Lindsay E Wu 14\r\n                              \r\n                            <\/p><p>\r\n                                <strong>\uff13\uff09Biomedicines. 2022 Jun 29;10(7):1544. doi: 10.3390\/biomedicines10071544<br>\r\n                                Unique Deep Radiomic Signature Shows NMN Treatment Reverses Morphology of Oocytes from Aged Mice<\/strong><br>\r\n                                Abbas Habibalahi 1,*, Jared M Campbell 1, Michael J Bertoldo 2,3, Saabah B Mahbub 1, Dale M Goss 3, William L Ledger 2, Robert B Gilchrist 2, Lindsay E Wu 3, Ewa M Goldys 1\r\n                                <\/p>\r\n                            <p>\r\n                              <strong>\uff14\uff092024 May;37(5):852-861. doi: 10.5713\/ab.23.0379. Epub 2024 Apr 1.<br>\r\n                              \u03b2-Nicotinamide mononucleotide improves chilled ram sperm quality in vitro by reducing oxidative stress damage<\/strong><br>\r\n                              Zhendong Zhu 1, Haolong Zhao 1, Qitai Yang 1, Yajing Li 1, RuYuan Wang 1, Adedeji Olufemi Adetunji 2, Lingjiang Min 1\r\n                            <\/p>\r\n                            <p class=\"mb100\">\r\n                              <strong>\uff15\uff09Antioxidants (Basel). 2024 Apr 24;13(5):507. doi: 10.3390\/antiox13050507<br>\r\n                              Supplementing Boar Diet with Nicotinamide Mononucleotide Improves Sperm Quality Probably through the Activation of the SIRT3 Signaling Pathway<\/strong><br>\r\n                              Haize Zhang 1, Jiawen Chai 1, Chaoyue Cao 1, Xiaolin Wang 1, Weijun Pang 1<br><br>\r\n                              Cell Rep\r\n                            <\/p>\r\n\r\n\r\n                              <!--<div class=\"funin_flow mb20\">\r\n                                  <p class=\"align_center bold pt10\">\u7ed9\u76f8\u5f53\u4e8e\u4eba\u7c7b60\u5c81\u768422\u4e2a\u6708\u5927\u7684\u8001\u9f20\u6ce8\u5c04\u4e86NMN\u3002<br>\r\n                                      \u7ed3\u679c\uff0c\u4e00\u5468\u540e\uff0c\u5b83\u7684\u808c\u8089\u53d8\u5f97\u50cf6\u4e2a\u6708\u5927\u7684\u5c0f\u9f20\u90a3\u6837\u3002<br>\r\n                                      \u8fd9\u76f8\u5f53\u4e8e\u4eba\u7c7b\u768420\u5c81\u3002<br>\r\n                                      \u4e5f\u5c31\u662f\u8bf4\uff0c\u5728\u77ed\u77ed\u7684\u4e00\u5468\u65f6\u95f4\u91cc\uff0c\u5b9e\u9645\u4e0a\u53d8\u5f97\u5e74\u8f7b\u4e8640\u5c81\u3002<\/p>\r\n                              <\/div>-->\r\n                              <p>\u5230\u76ee\u524d\u4e3a\u6b62\uff0cNMN\u8fd8\u6ca1\u6709\u53d1\u73b0\u4efb\u4f55\u8d1f\u9762\u6548\u679c\u3002<br>\r\n                                  \u4e0d\u4ec5\u5982\u6b64\uff0c\u5df2\u77e5\u5b83\u8fd8\u6709\u4fdd\u62a4\u773c\u775b\u3001\u542c\u529b\u3001\u809d\u810f\u548c\u5fc3\u810f\u7684\u4f5c\u7528\u3002<br>\r\n                                  \u867d\u7136\u5b83\u542c\u8d77\u6765\u50cf\u662f\u4e00\u79cd\u4e07\u80fd\u836f\uff0c\u4f46\u8fd9\u662f\u5168\u4e16\u754c\u7684\u7814\u7a76\u5b9e\u9a8c\u5ba4\u5df2\u7ecf\u786e\u8ba4\u7684\u4e8b\u5b9e\u3002<\/p>\r\n                              <p>\u8fd9\u79cd\u4f7f\u4eba\u6062\u590d\u9752\u6625\u7684\u6210\u5206NMN\u5728\u88ab\u8eab\u4f53\u5438\u6536\u540e\u4f1a\u8f6c\u5316\u4e3a\u4e00\u79cd\u53ebNAD+\u7684\u7269\u8d28\uff0c\u5e76\u4f20\u9012\u5230\u8eab\u4f53\u7684\u6bcf\u4e00\u4e2a\u89d2\u843d\u3002<br>\r\n                                  NAD+\u5b58\u5728\u4e8e\u6240\u6709\u751f\u7269\u7684\u4f53\u5185\uff0c\u5f71\u54cd\u9752\u6625\u548c\u5065\u5eb7\u7ef4\u6301\uff0c\u4f46\u4ece\u5341\u51e0\u5c81\u5f00\u59cb\u51cf\u5c11\uff0c\u523040\u5c81\u65f6\uff0c\u53ea\u5269\u4e0b\u9ad8\u5cf0\u65f6\u671f\u7684\u4e00\u534a\uff0c\u4f7f\u5f97\u8eab\u4f53\u5931\u53bb\u4e86\u9752\u6625\u7684\u6d3b\u529b\u3002<br>\r\n                                  \u56e0\u6b64\uff0c\u63d0\u9ad8\u4f53\u5185NAD+\u6d53\u5ea6\u7684\u65b9\u6cd5\u662f\u8865\u5145\u5176\u539f\u6599NMN\uff0c\u8fd9\u662f\u975e\u5e38\u6709\u6548\u7684\u3002<\/p>\r\n                              <p class=\"align_center\"><img decoding=\"async\" src=\"https:\/\/www.oakclinic-group.com\/wp\/wp-content\/themes\/oak-clinic\/assets\/images\/infertility\/decrease_cn.png\" alt=\"\u7531\u4e8e\u8870\u8001\uff0c\u4f53\u5185\u7684NAD+\u6c34\u5e73\u4e0b\u964d\"><\/p>\r\n                              <p>\u5f15\u81ea\u8bba\u6587\u300c<a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0042357\" target=\"_blank\" rel=\"noopener\">Age-Associated Changes In Oxdative Stress and NAD Metabolism InHuman Tissue Figure4<\/a>\u300d<\/p>\r\n                          <\/div>\r\n<div id=\"disease\">\r\n<\/div>\r\n<h2 class=\"section-dept__content02_title\">\r\n     \u53ef\u671f\u5f85\u6cbb\u7597\u6548\u679c\u7684\u75be\u75c5\r\n    <\/h2>\r\n<div class=\"section-dept__content02_text\">\r\n<ul class=\"list_type1\">\r\n<li>\r\n       \u8001\u5316\uff08\u6297\u8870\u8001\uff09\u2026\u6539\u5584\u589e\u52a0\u7684\u8001\u5316\u57fa\u56e0\u3002\r\n      <\/li>\r\n<li>\r\n       \u795e\u7ecf\u75be\u75c5\u2026\u6062\u590d\u795e\u7ecf\u75be\u75c5\u7279\u6709\u7684\u529f\u80fd\u969c\u788d\u3002\r\n      <\/li>\r\n<li>\r\n       \u7cd6\u5c3f\u75c5\u2026\u6062\u590d\u51cf\u5c11\u7684NAD+\uff0c\u6539\u5584\u8840\u7cd6\u5f02\u5e38\u3002\r\n      <\/li>\r\n<li>\r\n       \u7761\u7720\u8d28\u91cf\u63d0\u9ad8\u2026\u5bf9\u6df1\u5165\u6709\u6548\u7684\u7761\u7720\u6709\u76ca\u3002\r\n      <\/li>\r\n<li>\r\n       \u808c\u529b\u6539\u5584\u2026\u5982\u6b65\u884c\u901f\u5ea6\u548c\u63e1\u529b\u7b49\u7684\u6570\u503c\u663e\u8457\u6539\u5584\u3002\r\n      <\/li>\r\n<li>\r\n       \u773c\u529f\u80fd\u2026\u5bf9\u773c\u7684\u8001\u5316\u6709\u786e\u5b9a\u7684\u6548\u679c\u3002\r\n      <\/li>\r\n<li>\r\n       \u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u2026\u6709\u6548\u51cf\u5c11\u03b2-\u6dc0\u7c89\u6837\u86cb\u767d\u4ea7\u751f\u3001\u6dc0\u7c89\u6591\u548c\u7a81\u89e6\u4e27\u5931\u7b49\u3002\r\n      <\/li>\r\n<li>\r\n       \u8111\u51fa\u8840\u2026\u89e3\u51b3\u8001\u5316\u5bfc\u81f4\u7684\u8840\u7ba1\u529f\u80fd\u4e0d\u5168\u548c\u6297\u6c27\u5316\u6548\u679c\u3002\r\n      <\/li>\r\n<li>\r\n       \u80a5\u80d6\u53ca\u5176\u5e76\u53d1\u75c7\u2026\u901a\u8fc7\u6fc0\u6d3b\u7ebf\u7c92\u4f53\uff0c\u6539\u5584\u808c\u8089\u548c\u809d\u810f\u7684\u529f\u80fd\u3002\r\n      <\/li>\r\n<\/ul>\r\n<p class=\"align_center\">\r\n<img decoding=\"async\" alt=\"sirtuin\u4e0e\u8001\u5316\u76f8\u5173\u75be\u75c5\" src=\"https:\/\/www.oakclinic-group.com\/wp\/wp-content\/themes\/oak-clinic\/zh\/assets\/images\/infertility\/aging_diseases01.png\"\/>\r\n<\/p>\r\n<p class=\"align_center\">\r\n<img decoding=\"async\" alt=\"sirtuin\u4e0e\u8001\u5316\u76f8\u5173\u75be\u75c5\u56fe\u8868\" src=\"https:\/\/www.oakclinic-group.com\/wp\/wp-content\/themes\/oak-clinic\/zh\/assets\/images\/infertility\/aging_diseases02.png\"\/>\r\n<\/p>\r\n<p>\r\n      \u5f15\u81ea\u8bba\u6587\u300c\r\n      <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28068222\/\" target=\"_blank\" rel=\"noopener\">\r\n       Long-term administration of nicotinamide mononucleatidemitigates age assosiated physioligical decline in mice Figure1\r\n      <\/a>\r\n      \u300d\r\n     <\/p>\r\n<\/div>\r\n<div id=\"treatment\">\r\n<\/div>\r\n<h2 class=\"section-dept__content02_title\">\r\n     \u6cbb\u7597\u65b9\u6cd5\r\n    <\/h2>\r\n<div class=\"section-dept__content02_text\">\r\n<p>\r\n      \u5728\u5de6\u53f3\u4efb\u4e00\u624b\u81c2\u70b9\u6ef4\u542b\u6709NMN\u7684\u5236\u5242\u3002\u6240\u9700\u65f6\u95f4\u5927\u7ea6\u4e3a15\uff5e30\u5206\u949f\u3002\r\n     <\/p>\r\n<p>\r\n      \u203b\u5373\u4f7f\u53ea\u8fdb\u884c\u4e00\u6b21\u6cbb\u7597\u4e5f\u53ef\u4ee5\u770b\u5230\u67d0\u79cd\u6548\u679c\uff0c\u4f46\u5982\u679c\u76ee\u6807\u662f\u7ef4\u6301\u5065\u5eb7\u3001\u9632\u6b62\u8001\u5316\uff08\u6297\u8870\u8001\uff09\u6216\u6062\u590d\u75b2\u52b3\u7b49\uff0c\u5efa\u8bae\u6bcf1\uff5e4\u5468\u63a5\u53d7\u4e00\u6b21\u6cbb\u7597\u4ee5\u4fdd\u6301\u6548\u679c\u3002\r\n     <\/p>\r\n<\/div>\r\n<div id=\"side_effects\">\r\n<\/div>\r\n<h2 class=\"section-dept__content02_title\">\r\n     NMN\u70b9\u6ef4\u7684\u7981\u5fcc\u3001\u526f\u4f5c\u7528\r\n    <\/h2>\r\n<div class=\"section-dept__content02_text\">\r\n<p>\r\n      \u8840\u7ba1\u75bc\u75db\r\n     <\/p>\r\n<\/div>\r\n<div id=\"nmn_fees\">\r\n<\/div>\r\n<h2 class=\"section-dept__content02_title\">\r\n     NMN\u70b9\u6ef4\u7684\u8d39\u7528\r\n    <\/h2>\r\n<div class=\"section-dept__content02_text\">\r\n<p>\r\n      \u6bcf\u6b21 13,200\u65e5\u5143\uff08\u542b\u7a0e14,520\u65e5\u5143\uff09<\/p>\r\n<p>\r\n\u203b\u53e6\u52a0\u6536\u8bca\u5bdf\u8d39\u548c\u6ce8\u5c04\u64cd\u4f5c\u8d39\u3002<br>\r\n\u203bNMN\u70b9\u6ef4\u57282025\u5e742\u670828\u65e5\u4e4b\u524d\u8d39\u7528\u4e3a13,200\u65e5\u5143\uff08\u542b\u7a0e14,520\u65e5\u5143\uff09\uff0c\u4f46\u4ece2025\u5e743\u67081\u65e5\u8d77\uff0c\u8d39\u7528\u5c06\u8c03\u6574\u4e3a18,000\u65e5\u5143\uff08\u542b\u7a0e19,800\u65e5\u5143\uff09\u3002\r\n     <\/p>\r\n<\/div>\r\n<div id=\"quality\">\r\n<\/div>\r\n<h2 class=\"section-dept__content02_title\">\r\n     NMN\u539f\u6750\u6599\u7684\u8d28\u91cf\r\n    <\/h2>\r\n<div class=\"section-dept__content02_text\">\r\n<p>\r\n      \u6211\u4eec\u533b\u9662\u4f7f\u7528\u7684NMN\u70b9\u6ef4\u9009\u7528\u7ecf\u7814\u7a76\u8bc1\u5b9e\u5b89\u5168\u6027\u4e14\u8bc1\u660e\u80fd\u589e\u52a0\u8840\u4e2dNAD+\u7684\u552f\u4e00NMN\u539f\u6750\u6599\u201cN-Pro Med\u2122\uff08\u7531Nordest\u516c\u53f8\u5236\u9020\uff09\u201d\uff0c\u5176\u751f\u4ea7\u8fc7\u7a0b\u4e25\u683c\u4fdd\u6301\u8d28\u91cf\uff0c\u5e76\u8fdb\u884c\u751f\u4ea7\u7ba1\u7406\u3002\u6548\u679c\u5df2\u88ab\u540e\u85e4\u7ae0\u66a2\u6559\u6388\uff08\u5175\u5e93\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\uff09\u7b49\u4eba\u5728\u7814\u7a76\u4e2d\u8bc1\u5b9e\uff0c\u5982\u4e0b\u6240\u793a\uff1a\r\n      <br\/>\r\n      \u5f8c\u85e4\u7ae0\u66a2\u6559\u6388\uff08\u5175\u5eab\u533b\u79d1\u5927\u5b66 \u533b\u5b66\u90e8\uff09\u3089\u306b\u3088\u308b\u7814\u7a76\u3067\u78ba\u8a8d\u3055\u308c\u305f\u52b9\u679c\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002\r\n     <\/p>\r\n<h3 class=\"section-dept__content03_title\">\r\n      \u8bba\u6587\u6458\u8981\uff1a\u9a8c\u8bc1\u9759\u8109\u5185\u6ce8\u5c04300mg NMN\u7684\u5b89\u5168\u6027\u3002\u8ba4\u4e3a\u9759\u8109\u5185NMN\u6ce8\u5c04\u662f\u5b89\u5168\u4e14\u6709\u76ca\u7684\u3002\r\n     <\/h3>\r\n<h4 class=\"section-top__guide_title\">\r\n      \u6709\u6548\u6027\r\n     <\/h4>\r\n<ul class=\"list_type1\">\r\n<li>\r\n       \u8840\u6db2\u4e2d\u7684\u957f\u5bff\u5206\u5b50NAD+\u6c34\u5e73\u4e0a\u5347\u7ea620%\uff08\u53c2\u89c1NAD+\u6c34\u5e73\u56fe\uff09\r\n      <\/li>\r\n<li>\r\n       \u6539\u5584\u7761\u7720\u8d28\u91cf\r\n      <\/li>\r\n<li>\r\n       \u8840\u6db2\u4e2d\u8102\u80aa\uff08TG\u6c34\u5e73\uff09\u4e0b\u964d\u7ea675%\uff08\u53c2\u89c1TG\u6c34\u5e73\u56fe\uff09\r\n      <\/li>\r\n<li>\r\n       \u7531\u4e8eTG\u6c34\u5e73\u7684\u6539\u5584\uff0c\u6709\u53ef\u80fd\u9884\u9632\u548c\u6cbb\u7597\u8102\u80aa\u809d\u548c\u4e0e\u7cd6\u5c3f\u75c5\u76f8\u5173\u7684\u75be\u75c5\r\n      <\/li>\r\n<\/ul>\r\n<p>\r\n      \u7279\u522b\u662f\uff0c\u70b9\u6ef4\u540e\u8840\u6db2\u4e2d\u7684\u8102\u80aa\u51cf\u5c11\u7ea675%\u7684\u6548\u679c\uff0c\u5728\u4e4b\u524d\u7684NMN\u53e3\u670d\u7814\u7a76\u4e2d\u5c1a\u672a\u786e\u8ba4\uff0c\u88ab\u8ba4\u4e3a\u662fNMN\u70b9\u6ef4\u7684\u72ec\u7279\u6548\u679c\u3002\r\n     <\/p>\r\n<p class=\"align_center\">\r\n<img decoding=\"async\" alt=\"TG\u6c34\u5e73\u56fe\" src=\"https:\/\/www.oakclinic-group.com\/wp\/wp-content\/themes\/oak-clinic\/zh\/assets\/images\/infertility\/tg_level_grapph.png\"\/>\r\n<\/p>\r\n<p class=\"align_center\">\r\n<img decoding=\"async\" alt=\"NAD+\u6c34\u5e73\u56fe\" src=\"https:\/\/www.oakclinic-group.com\/wp\/wp-content\/themes\/oak-clinic\/zh\/assets\/images\/infertility\/nad_graph.png\"\/>\r\n<\/p>\r\n<p>\r\n      \u53c2\u8003\u6587\u732e\uff1a\r\n      <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36225528\/\" target=\"_blank\" rel=\"noopener\">\r\n       Kimura et al., 2022 | Cureus Nicotinamide Mononucleotide Is Safety Metabolized and Signiflacantly Reduces Blood Triglyceride Levels in Healthy Individuals\r\n      <\/a>\r\n<br\/>\r\n      \uff0a\u8fd9\u6307\u7684\u662f\u5728\u8fd9\u7bc7\u6587\u7ae0\u53d1\u5e03\u4e4b\u524d\uff0c\u5e76\u672a\u6709\u62a5\u544a\u6307\u51faNMN\u70b9\u6ef4\u6709\u76f8\u540c\u7684\u6548\u679c\u3002\r\n     <\/p>\r\n<\/div>\r\n<div id=\"treatise\">\r\n<\/div>\r\n<h2 class=\"section-dept__content02_title\">\r\n     \u53c2\u8003\u6587\u732e\r\n    <\/h2>\r\n<div class=\"section-dept__content02_text\">\r\n<ul class=\"list_type1\">\r\n<li>\r\n<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9628229\/#\" target=\"_blank\" rel=\"noopener\">\r\n        Cell Prolif.\r\n       <\/a>\r\n       2022 Nov; 55(11): e13303.\r\n       <br\/>\r\n       Published online 2022 Jul 10. doi:\r\n       <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cpr.13303\" target=\"_blank\" rel=\"noopener\">\r\n        10.1111\/cpr.13303\r\n       <\/a>\r\n<br\/>\r\n       PMCID: PMC9628229\r\n       <br\/>\r\n       PMID:\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35811338\/\" target=\"_blank\" rel=\"noopener\">\r\n        35811338\r\n       <\/a>\r\n<br\/>\r\n       Administration of nicotinamide mononucleotide improves oocyte quality of obese mice\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Wang%20L%5BAuthor%5D\" target=\"_blank\" rel=\"noopener\">\r\n        Luyao Wang\r\n       <\/a>\r\n       , 1 , 2\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Chen%20Y%5BAuthor%5D\" target=\"_blank\" rel=\"noopener\">\r\n        Yurong Chen\r\n       <\/a>\r\n       , 1 , 2\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Wei%20J%5BAuthor%5D\" target=\"_blank\" rel=\"noopener\">\r\n        Jiarui Wei\r\n       <\/a>\r\n       , 1 , 2\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Guo%20F%5BAuthor%5D\" target=\"_blank\" rel=\"noopener\">\r\n        Fucheng Guo\r\n       <\/a>\r\n       , 1 , 2\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Li%20L%5BAuthor%5D\" target=\"_blank\" rel=\"noopener\">\r\n        Leyi Li\r\n       <\/a>\r\n       , 1 , 2\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Han%20Z%5BAuthor%5D\" target=\"_blank\" rel=\"noopener\">\r\n        Zhen Han\r\n       <\/a>\r\n       , 1 , 2\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Wang%20Z%5BAuthor%5D\" target=\"_blank\" rel=\"noopener\">\r\n        Zhengzhu Wang\r\n       <\/a>\r\n       , 1 , 2\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Zhu%20H%5BAuthor%5D\" target=\"_blank\" rel=\"noopener\">\r\n        Haibo Zhu\r\n       <\/a>\r\n       , 3\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Zhang%20X%5BAuthor%5D\" target=\"_blank\" rel=\"noopener\">\r\n        Xiaoling Zhang\r\n       <\/a>\r\n       , 1 , 2\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Li%20Z%5BAuthor%5D\" target=\"_blank\" rel=\"noopener\">\r\n        Ziyi Li\r\n       <\/a>\r\n       , 1 , 2 and\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Dai%20X%5BAuthor%5D\" target=\"_blank\" rel=\"noopener\">\r\n        Xiangpeng Dai\r\n       <\/a>\r\n       1 , 2\r\n       <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9628229\/#\" target=\"_blank\" rel=\"noopener\">\r\n        Author information Article notes Copyright and License information PMC Disclaimer\r\n       <\/a>\r\n<\/li>\r\n<li class=\"mt20\">\r\n       Cell Prolif. 2023 Aug;56(8):e13419. doi: 10.1111\/cpr.13419. Epub 2023 Feb 9.\r\n       <br\/>\r\n<strong>\r\n        Nicotinamide mononucleotide restores oxidative stress-related apoptosis of oocyte exposed to benzyl butyl phthalate in mice\r\n       <\/strong>\r\n<br\/>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Jiang+Y&amp;cauthor_id=36756972\" target=\"_blank\" rel=\"noopener\">\r\n        Yi Jiang\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-1\" target=\"_blank\" rel=\"noopener\">\r\n        1\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-2\" target=\"_blank\" rel=\"noopener\">\r\n        2\r\n       <\/a>\r\n       ,\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Wang+D&amp;cauthor_id=36756972\">\r\n        Di Wang\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-1\" target=\"_blank\" rel=\"noopener\">\r\n        1\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-2\" target=\"_blank\" rel=\"noopener\">\r\n        2\r\n       <\/a>\r\n       ,\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Zhang+C&amp;cauthor_id=36756972\" target=\"_blank\" rel=\"noopener\">\r\n        Cheng Zhang\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-1\">\r\n        1\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-2\">\r\n        2\r\n       <\/a>\r\n       ,\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Jiao+Y&amp;cauthor_id=36756972\">\r\n        Yangyang Jiao\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-1\" target=\"_blank\" rel=\"noopener\">\r\n        1\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-2\" target=\"_blank\" rel=\"noopener\">\r\n        2\r\n       <\/a>\r\n       ,\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Pu+Y&amp;cauthor_id=36756972\" target=\"_blank\" rel=\"noopener\">\r\n        Yanan Pu\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-1\">\r\n        1\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-2\" target=\"_blank\" rel=\"noopener\">\r\n        2\r\n       <\/a>\r\n       ,\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Cheng+R&amp;cauthor_id=36756972\">\r\n        Rong Cheng\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-1\">\r\n        1\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-2\">\r\n        2\r\n       <\/a>\r\n       ,\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Li+C&amp;cauthor_id=36756972\" target=\"_blank\" rel=\"noopener\">\r\n        Chunyu Li\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-1\" target=\"_blank\" rel=\"noopener\">\r\n        1\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-2\" target=\"_blank\" rel=\"noopener\">\r\n        2\r\n       <\/a>\r\n       ,\r\n       <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Chen+Y&amp;cauthor_id=36756972\" target=\"_blank\" rel=\"noopener\">\r\n        Yan Chen\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-1\" target=\"_blank\" rel=\"noopener\">\r\n        1\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-2\" target=\"_blank\" rel=\"noopener\">\r\n        2\r\n       <\/a>\r\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36756972\/#full-view-affiliation-3\" target=\"_blank\" rel=\"noopener\">\r\n        3\r\n       <\/a>\r\n<br\/>\r\n       Affiliations expand\r\n       <ul>\r\n<li>\r\n 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