IFCE Technique

Other Approaches

Intrauterine administration of granulocyte colony-stimulating factor (G-CSF) preparation for thin endometrium.

Note: About 90% of successful embryo implantations occur at the bottom of the uterus.

Generally speaking, endometrial implantation requires an endometrial thickness of 7 mm or more. The G-CSF preparation is a domestically approved injection (granulocyte-increasing effect) and is widely used in daily medical care. It was reported that for infertile women with thin endometrium, G-CSF into the uterine lumen prior to embryo transfer improved the thickness of the endometrium and significantly improved the pregnancy rate. (Gleicher N, et al., Fertility and Sterility 2011; 95: 2123.e13-e17.). For patients whose endometrial thickness remains thin by the conventional methods, G-CSF is administered to the uterine lumen with patient informed consent.

Intrauterine administration of human chorionic gonadotropin (HCG)

Immediately before embryo transfer of HCG is also used which further improves the chance of success (Mansour R, et al., Fertility and Sterility 2011; 96: 1370-1374.e1.) Ask one of our doctors if this is recommended for you.