Pioneer of infertility treatment. Covering the needs of infertility from various tests 
to IVF/ICSI’s Advanced Reproductive Technologies.

〔Sumiyoshi&Ginza〕Long-term Culture, Blastocyst Culture

This is the method of transfer and cryopreservation of the developed embryo and blastocyst after OPU and culturing to Day 4, 7.  We will be able to remove the embryos that stop splitting in the early term and strictly sort the good embryos.


The zygote will repeat the cell division and will continue to develop.  By Day 3˜ 4, the number of cells will increase each time the cell divides, and the size of one cell will become smaller.  After that, groups of cells will adhere to one another, and when it goes through the state of compaction where the surfaces of the cell are connected then it will become the blastocyst.  Because the nutrients that are necessary for the early embryo and the embryo and blastocyst that occur after compaction will differ, when it comes to long-term culture, we will change the culture solution on the 3rd day.



Day 0 Day 1 Day 2 Day 3 Day 4 Day 5
Oocyte Pick-up~ Dividing stsge Compaction~ Blastocyst

Pyruvic acid is the source of energy of the early embryo

In the case of people it will become a compaction after 16 cells and the energy
source will change to glucose

↓ ↓

Culture Solution including much pyruvic acid

Culture Solution including much glucose

equal equal

Organization close to the fallopian tubal fluid of people

Organization close to the uterus.



Page Top

Oak Medical Group has been from the time we opened, supporting the many issues of women's health, building performance and trust, and not only here in Osaka, but centering in Kansai we are receiving patients from across Japan.
Especially with our infertility treatment, we are widely covering the various tests to IVF/ICSI's Advanced Reproductive Technologies.  Depending on the cause of the infertility, we are handling the treatment of each patient one by one.  If you have some concerns, please don't hesitate to consult with us.