{"id":1255,"date":"2024-10-08T19:46:42","date_gmt":"2024-10-08T10:46:42","guid":{"rendered":"https:\/\/www.oakclinic-group.com\/wp\/brca\/"},"modified":"2024-10-09T12:59:09","modified_gmt":"2024-10-09T03:59:09","slug":"brca","status":"publish","type":"page","link":"https:\/\/www.oakclinic-group.com\/en\/infertility\/brca\/","title":{"rendered":"Comprehensive Cancer Susceptibility Testing (BRCA 1 and 2 testing)"},"content":{"rendered":"<div class=\"section-dept__container\">\n<div class=\"section-dept__first_content\">\n<section class=\"section-dept__content01\">\n<h1 class=\"section-dept__content01_title\">\n     Comprehensive Cancer Susceptibility Testing\n     <span class=\"rem28\">\n      (BRCA 1 and 2 testing)\n     <\/span>\n<\/h1>\n<!-- \u5404\u30af\u30ea\u30cb\u30c3\u30af -->\n<div class=\"float_right mt30\">\n<span class=\"text_frame2\">\n<a href=\"https:\/\/www.oakclinic-group.com\/en\/sumiyoshi\/\">\n       Sumiyoshi\n      <\/a>\n<\/span>\n<span class=\"text_frame2\">\n<a href=\"https:\/\/www.oakclinic-group.com\/en\/umeda_ladys\/\">\n       Umeda\n      <\/a>\n<\/span>\n<span class=\"text_frame2\">\n<a href=\"https:\/\/www.oakclinic-group.com\/en\/ginza_ladys\/\">\n       Ginza\n      <\/a>\n<\/span>\n<\/div>\n<p style=\"clear: both;\">\n<\/p>\n<!-- \u5404\u30af\u30ea\u30cb\u30c3\u30af \u3053\u3053\u307e\u3067 -->\n<div class=\"section-dept__content01_text\">\n<div class=\"section-dept__content02_text\">\n<p>\n       Comprehensive cancer susceptibility testing (BRCA1, BRCA2 gene test) tests for the presence of BRCA1 or BRCA2 mutations that are associated with cancer development (cancer risk).\n       <br\/>\n       BRCA proteins are proteins that repair mutations in DNA (deoxyribonucleic acid).\n       <br\/>\n       Therefore, if either the BRCA1 or BRCA2 gene is mutated, an abnormal BRCA protein is produced.\n       <br\/>\n       Inheritance of a mutated BRCA gene tends to increase the probability of developing breast and ovarian cancer at a younger age than inheritance of a normal (unmutated) BRCA gene.\n       <br\/>\n       For details, please click the button below.\n      <\/p>\n<div class=\"section-dept__guide_btn_area mt60\">\n<ul class=\"mb10\">\n<li class=\"section-dept__guide_btn guide_btn_w\">\n<a href=\"https:\/\/www.oakclinic-group.com\/en\/funin\/brca\/\" target=\"_blank\" rel=\"noopener\">\n<p>\n           Comprehensive Cancer Susceptibility Testing\n           <br\/>\n           (BRCA 1 and 2 testing)\n          <\/p>\n<\/a>\n<\/li>\n<\/ul>\n<\/div>\n<div class=\"section-dept__content02_text mt60\">\n<h4 class=\"section-top__guide_title\">\n        [Reference] Breast Cancer Risk\n       <\/h4>\n<div class=\"fee_box\">\n<table>\n<tbody>\n<tr>\n<th>\n            Group Type\n           <\/th>\n<th>\n            Probability of Occurrence\n           <\/th>\n<\/tr>\n<tr>\n<td class=\"color_gray\" data-label=\"Collective type\">\n            Probability of developing breast cancer in the population of the general female population\n           <\/td>\n<td data-label=\"Occurrence probability\">\n            About 12% over the course of a lifetime\n           <\/td>\n<\/tr>\n<tr>\n<td class=\"color_gray\" data-label=\"Collective type\">\n            Women who have inherited a harmful BRCA1 mutation\n           <\/td>\n<td data-label=\"Occurrence probability\">\n            Estimated at about 72% by age 80\n            <br\/>\n            Approximately 40% chance of developing breast cancer in the other breast within 20 years of diagnosis\n           <\/td>\n<\/tr>\n<tr>\n<td class=\"color_gray\" data-label=\"Collective type\">\n            Women who have inherited a harmful BRCA2 mutation\n           <\/td>\n<td data-label=\"Occurrence probability\">\n            Estimated at about 69% by age 80\n            <br\/>\n            Approximately 26% chance of developing breast cancer in the other breast within 20 years of diagnosis\n           <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h4 class=\"section-top__guide_title mt50\">\n        [Reference]Ovarian Cancer Risk\n       <\/h4>\n<div class=\"fee_box\">\n<table>\n<tbody>\n<tr>\n<th>\n            Group Type\n           <\/th>\n<th>\n            Probability of Occurrence\n           <\/th>\n<\/tr>\n<tr>\n<td class=\"color_gray\" data-label=\"Collective type\">\n            Probability of developing ovarian cancer in the population of the general female population\n           <\/td>\n<td data-label=\"Occurrence probability\">\n            About 1.3% over the course of a lifetime\n           <\/td>\n<\/tr>\n<tr>\n<td class=\"color_gray\" data-label=\"Collective type\">\n            Women who have inherited a harmful BRCA1 mutation\n           <\/td>\n<td data-label=\"Occurrence probability\">\n            Estimated at about 44% by age 80\n           <\/td>\n<\/tr>\n<tr>\n<td class=\"color_gray\" data-label=\"Collective type\">\n            Women who have inherited a harmful BRCA2 mutation\n           <\/td>\n<td data-label=\"Occurrence probability\">\n            Estimated at about 69% by age 80\n           <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: right; font-size: 0.85em;\">\n         Source\uff1a\n         <a href=\"https:\/\/hbcr-survival.ganjoho.jp\/\" target=\"_blank\" rel=\"noopener\">\n          National Cancer Center Cancer Information Service \"In-Hospital Cancer Registration Survival Rate Statistics\"\n         <\/a>\n<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"Comprehensive Cancer Susceptibility Testing (BRCA 1 and 2 testing) Sumiyoshi Umeda Ginza Comprehensive cancer susceptibility testing (BRCA1, BRCA2 gene test) tests for the presence of BRCA1 or BRCA2 mutations that are associated with cancer development (cancer risk). BRCA proteins are proteins that repair mutations in DNA (deoxyribonucleic acid). Therefore, if either the BRCA1 or BRCA2 [&hellip;]","protected":false},"author":2,"featured_media":0,"parent":1253,"menu_order":363,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_locale":"en_US","_original_post":"https:\/\/www.oakclinic-group.com\/wp\/?page_id=597","footnotes":""},"class_list":["post-1255","page","type-page","status-publish","hentry","en-US"],"_links":{"self":[{"href":"https:\/\/www.oakclinic-group.com\/wp-json\/wp\/v2\/pages\/1255","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.oakclinic-group.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.oakclinic-group.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.oakclinic-group.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.oakclinic-group.com\/wp-json\/wp\/v2\/comments?post=1255"}],"version-history":[{"count":3,"href":"https:\/\/www.oakclinic-group.com\/wp-json\/wp\/v2\/pages\/1255\/revisions"}],"predecessor-version":[{"id":2484,"href":"https:\/\/www.oakclinic-group.com\/wp-json\/wp\/v2\/pages\/1255\/revisions\/2484"}],"up":[{"embeddable":true,"href":"https:\/\/www.oakclinic-group.com\/wp-json\/wp\/v2\/pages\/1253"}],"wp:attachment":[{"href":"https:\/\/www.oakclinic-group.com\/wp-json\/wp\/v2\/media?parent=1255"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}