{"id":6834,"date":"2021-02-11T17:03:15","date_gmt":"2021-02-11T08:03:15","guid":{"rendered":"https:\/\/www.oakclinic-group.com\/blog\/?p=6834"},"modified":"2021-02-11T17:03:15","modified_gmt":"2021-02-11T08:03:15","slug":"%e7%b2%be%e5%ad%90%e3%81%ae%e5%89%8d%e9%80%b2%e9%81%8b%e5%8b%95%e3%81%ab%e9%96%a2%e3%82%8f%e3%82%8b%e9%81%ba%e4%bc%9d%e5%ad%90tdrg1","status":"publish","type":"post","link":"https:\/\/www.oakclinic-group.com\/blog\/2021\/02\/11\/%e7%b2%be%e5%ad%90%e3%81%ae%e5%89%8d%e9%80%b2%e9%81%8b%e5%8b%95%e3%81%ab%e9%96%a2%e3%82%8f%e3%82%8b%e9%81%ba%e4%bc%9d%e5%ad%90tdrg1\/","title":{"rendered":"\u7cbe\u5b50\u306e\u524d\u9032\u904b\u52d5\u306b\u95a2\u308f\u308b\u907a\u4f1d\u5b50TDRG1"},"content":{"rendered":"\n<p>\u80da\u57f9\u990a\u58eb\u306e\u5965\u5e73\u88d5\u4e00\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4e0d\u598a\u75c7\u306e\u7d0450%\u306f\u7537\u6027\u4e0d\u598a\u3068\u8a00\u308f\u308c\u3001\u7537\u6027\u4e0d\u598a\u306e\u767a\u751f\u7387\u306f\u904e\u53bb\u6570\u5341\u5e74\u306b\u308f\u305f\u3063\u3066\u5897\u52a0\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7cbe\u5b50\u7121\u529b\u75c7\uff08\u5168\u4f53\u306e\u904b\u52d5\u7387\u304c40%\u672a\u6e80\u307e\u305f\u306f\u524d\u9032\u904b\u52d5\u7cbe\u5b50\u306e\u5272\u5408\u304c32\uff05\u672a\u6e80\uff09\u306f\u3001\u7537\u6027\u4e0d\u598a\u306e\u4e3b\u306a\u539f\u56e0\u306e\u4e00\u3064\u3067\u3059\u3002\u3053\u308c\u307e\u3067\u306b\u7cbe\u5b50\u306e\u904b\u52d5\u6027\u3092\u8abf\u7bc0\u3059\u308b\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u3064\u3044\u3066\u5e45\u5e83\u3044\u7814\u7a76\u304c\u884c\u308f\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u7cbe\u5b50\u7121\u529b\u75c7\u306e\u75c5\u614b\u306f\u307e\u3060\u5b8c\u5168\u306b\u306f\u89e3\u660e\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u6700\u8fd1\u5831\u544a\u3055\u308c\u305f\u3053\u306e\u8ad6\u6587\u3067\u306f\u3001\u30d2\u30c8\u7cbe\u5de3\u306b\u7279\u7570\u7684\u306b\u767a\u73fe\u3057\u3066\u3044\u308b\u7cbe\u5de3\u767a\u751f\u95a2\u9023\u907a\u4f1d\u5b501\uff08<em>TDRG1<\/em>\uff09\u306b\u6ce8\u76ee\u3057\u3001TDRG1\u3068\u30d2\u30c8\u7cbe\u5b50\u306e\u904b\u52d5\u6027\u3068\u306e\u95a2\u9023\u3092\u8abf\u3079\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>Testis developmental related gene 1 (TDRG1) encodes a progressive motility-associated protein in human spermatozoa<\/p>\n\n\n\n<p>Human Reproduction, Volume 36, Issue 2, February 2021, Pages 283\u2013292, https:\/\/doi.org\/10.1093\/humrep\/deaa297<\/p>\n\n\n\n<p>\u5bfe\u8c61\u30fb\u65b9\u6cd5<\/p>\n\n\n\n<p>\u7cbe\u5b50\u30b5\u30f3\u30d7\u30eb\u306f\u30012018\u5e742\u6708\u304b\u30892019\u5e741\u6708\u306b\u4e2d\u56fd\u306e\u3042\u308b\u751f\u6b96\u533b\u7642\u30bb\u30f3\u30bf\u30fc\u3092\u8a2a\u308c\u305f\u6b63\u5e38\u7cbe\u5b50\u7537\u6027\uff0827\u4eba\uff09\u3068\u7cbe\u5b50\u7121\u529b\u75c7\u7537\u6027\uff0825\u4eba\uff09\u304b\u3089\u63a1\u53d6\u3055\u308c\u307e\u3057\u305f\u3002\u305d\u308c\u305e\u308c\u306e\u7cbe\u5b50\u306eTDRG1\u767a\u73fe\u30ec\u30d9\u30eb\u3001\u524d\u9032\u904b\u52d5\u6027\u3092\u6bd4\u8f03\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u7d30\u80de\u900f\u904e\u6027\u30da\u30d7\u30c1\u30c9\uff08CPP\uff09\u3092\u7528\u3044\u3066\u4eba\u70ba\u7684\u306bTDRG1\u3092\u7cbe\u5b50\u306b\u5c0e\u5165\u3057\u3001\u524d\u9032\u904b\u52d5\u6027\u306e\u5909\u5316\u3092\u8a55\u4fa1\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001TDRG1\u3068\u4ed6\u306e\u7cbe\u5b50\u904b\u52d5\u95a2\u9023\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u306e\u95a2\u308f\u308a\u306b\u3064\u3044\u3066\u3082\u8abf\u3079\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7d50\u679c<\/p>\n\n\n\n<p>TDRG1\u306e\u5e73\u5747\u30ec\u30d9\u30eb\u306f\u3001\u7cbe\u5b50\u7121\u529b\u75c7\u306e\u7537\u6027\u306e\u7cbe\u5b50\u3067\u306f\u6b63\u5e38\u7537\u6027\u306e\u7cbe\u5b50\u3068\u6bd4\u8f03\u3057\u3066\u6709\u610f\u306b\u6e1b\u5c11\u3057\uff08P &lt; 0.05\uff09\u3001\u524d\u9032\u904b\u52d5\u7cbe\u5b50\u306e\u5272\u5408\u3068\u6b63\u306e\u76f8\u95a2\u304c\u3042\u308a\u307e\u3057\u305f\uff08r<sup>2<\/sup> = 0.75\u3001P = 0.0001\uff09\u3002<\/p>\n\n\n\n<p>CPP\u3092\u7528\u3044\u305f\u7cbe\u5b50\u3078\u306eTDRG1\u306e\u5c0e\u5165\u306f\u3001\u524d\u9032\u904b\u52d5\u6027\u3092\u6709\u610f\u306b\u5897\u52a0\u3055\u305b\uff08P &lt; 0.05\uff09\u3001\u7cbe\u5b50\u7121\u529b\u75c7\u306e\u7537\u6027\u304b\u3089\u6b63\u5e38\u30ec\u30d9\u30eb\u3078\u306e\u7cbe\u5b50\u306e\u524d\u9032\u904b\u52d5\u6027\u3092\u6539\u5584\u3057\u307e\u3057\u305f\uff0821.6%\u304b\u308932.5%\uff09\u3002<\/p>\n\n\n\n<p>TDRG1\u306f\u3001\u4ed6\u306e\u7cbe\u5b50\u904b\u52d5\u6027\u95a2\u9023\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u30bf\u30f3\u30d1\u30af\u8cea\u8907\u5408\u4f53\u3092\u5f62\u6210\u3057\u3001TDRG1\u306e\u767a\u73fe\u4f4e\u4e0b\u306f\u4ed6\u306e\u7cbe\u5b50\u904b\u52d5\u6027\u95a2\u9023\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6e1b\u5c11\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u89e3\u8aac<\/p>\n\n\n\n<p>\u7d041000\u500b\u306e\u907a\u4f1d\u5b50\u304c\u30d2\u30c8\u306e\u7cbe\u5de3\u3067\u306e\u307f\u767a\u73fe\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u308c\u3089\u306e\u591a\u304f\u306e\u6a5f\u80fd\u306f\u307e\u3060\u308f\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u3002\u8457\u8005\u3089\u306f\u4ee5\u524d\u306e\u7814\u7a76\u3067\u3001\u65b0\u305f\u306a\u30d2\u30c8\u7cbe\u5de3\u7279\u7570\u7684\u907a\u4f1d\u5b50\u3067\u3042\u308bTDRG1\u3092\u540c\u5b9a\u3057\u3066\u3044\u307e\u3059\u3002TDRG1\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001\u7cbe\u5b50\u5f62\u6210\u5f8c\u671f\u306e\u7cbe\u5b50\u7d30\u80de\u306b\u591a\u304f\u5b58\u5728\u3057\u3001\u30d2\u30c8\u7cbe\u5b50\u306e\u4e2d\u7247\u90e8\u3001\u4e3b\u90e8\u3001\u97ad\u6bdb\u306b\u5c40\u5728\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u5c40\u5728\u304b\u3089\u3001\u30d2\u30c8\u7cbe\u5b50\u306e\u904b\u52d5\u6027\u306e\u8abf\u7bc0\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u304c\u3001TDRG1\u306e\u751f\u7406\u5b66\u7684\u5f79\u5272\u306f\u89e3\u660e\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u672c\u7814\u7a76\u306b\u3088\u308a\u3001\u7cbe\u5b50\u306b\u304a\u3051\u308bTDRG1\u306e\u767a\u73fe\u306f\u3001\u6b63\u5e38\u7537\u6027\u3068\u6bd4\u8f03\u3057\u3066\u7cbe\u5b50\u7121\u529b\u75c7\u306e\u7537\u6027\u3067\u306f\u4f4e\u4e0b\u3057\u3066\u304a\u308a\u3001\u7cbe\u5b50\u306e\u524d\u9032\u904b\u52d5\u6027\u3068\u6b63\u306e\u76f8\u95a2\u304c\u3042\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u307e\u305f\u3001TDRG1\u306e\u767a\u73fe\u4f4e\u4e0b\u306f\u3001\u4ed6\u306e\u7cbe\u5b50\u904b\u52d5\u6027\u95a2\u9023\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u767a\u73fe\u30ec\u30d9\u30eb\u306b\u3082\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3001\u7d50\u679c\u7684\u306b\u7cbe\u5b50\u306e\u904b\u52d5\u6027\u306b\u4e0d\u53ef\u6b20\u306a\u7d4c\u8def\u3092\u963b\u5bb3\u3059\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u7d50\u679c\u306f\u3001\u7cbe\u5b50\u306e\u904b\u52d5\u6027\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u65b0\u305f\u306a\u77e5\u898b\u3092\u4e0e\u3048\u3001\u7cbe\u5b50\u7121\u529b\u75c7\u306e\u8a3a\u65ad\u30fb\u6cbb\u7642\u306b\u8ca2\u732e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignleft size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.oakclinic-group.com\/blog\/wp-content\/uploads\/2020\/02\/160107_inspection_kate.jpg\" alt=\"\" class=\"wp-image-1062\" width=\"260\" height=\"167\" srcset=\"https:\/\/www.oakclinic-group.com\/blog\/wp-content\/uploads\/2020\/02\/160107_inspection_kate.jpg 301w, https:\/\/www.oakclinic-group.com\/blog\/wp-content\/uploads\/2020\/02\/160107_inspection_kate-281x180.jpg 281w\" sizes=\"(max-width: 260px) 100vw, 260px\" \/><\/figure><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u80da\u57f9\u990a\u58eb\u306e\u5965\u5e73\u88d5\u4e00\u3067\u3059\u3002 \u4e0d\u598a\u75c7\u306e\u7d0450%\u306f\u7537\u6027\u4e0d\u598a\u3068\u8a00\u308f\u308c\u3001\u7537\u6027\u4e0d\u598a\u306e\u767a\u751f\u7387\u306f\u904e\u53bb\u6570\u5341\u5e74\u306b\u308f\u305f\u3063\u3066 &hellip;<\/p>\n","protected":false},"author":1,"featured_media":1062,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u7cbe\u5b50\u306e\u524d\u9032\u904b\u52d5\u306b\u95a2\u308f\u308b\u907a\u4f1d\u5b50TDRG1 | \u533b\u7642\u6cd5\u4eba\u30aa\u30fc\u30af\u4f1a\u3000\u4e0d\u598a\u30d6\u30ed\u30b0<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.oakclinic-group.com\/blog\/2021\/02\/11\/\u7cbe\u5b50\u306e\u524d\u9032\u904b\u52d5\u306b\u95a2\u308f\u308b\u907a\u4f1d\u5b50tdrg1\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" 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