{"id":6810,"date":"2021-01-28T15:31:28","date_gmt":"2021-01-28T06:31:28","guid":{"rendered":"https:\/\/www.oakclinic-group.com\/blog\/?p=6810"},"modified":"2021-01-28T15:31:28","modified_gmt":"2021-01-28T06:31:28","slug":"%e7%b2%be%e5%ad%90%e3%83%9f%e3%83%88%e3%82%b3%e3%83%b3%e3%83%89%e3%83%aa%e3%82%a2dna%e3%81%ab%e3%82%88%e3%82%8b%e5%a6%8a%e5%a8%a0%e4%ba%88%e6%b8%ac","status":"publish","type":"post","link":"https:\/\/www.oakclinic-group.com\/blog\/2021\/01\/28\/%e7%b2%be%e5%ad%90%e3%83%9f%e3%83%88%e3%82%b3%e3%83%b3%e3%83%89%e3%83%aa%e3%82%a2dna%e3%81%ab%e3%82%88%e3%82%8b%e5%a6%8a%e5%a8%a0%e4%ba%88%e6%b8%ac\/","title":{"rendered":"\u7cbe\u5b50\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2DNA\u306b\u3088\u308b\u598a\u5a20\u4e88\u6e2c"},"content":{"rendered":"\n<p>\u80da\u57f9\u990a\u58eb\u306e\u5965\u5e73\u88d5\u4e00\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u7d30\u80de\u304c\u6301\u3064DNA\u306b\u306f\u3001\u6838DNA\u3068\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2DNA\u306e2\u7a2e\u985e\u3042\u308a\u307e\u3059\u3002\u901a\u5e381\u7d30\u80de\u3042\u305f\u308a\u3001\u6838DNA\u306f2\u30b3\u30d4\u30fc\uff08\u7236\u6bcd\u305d\u308c\u305e\u308c\u306e\u30b2\u30ce\u30e0\u7531\u6765\uff09\u3067\u3059\u304c\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2DNA\u306f\u6570\u5343\u30b3\u30d4\u30fc\uff081\u3064\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3042\u305f\u308a\u6570\u30b3\u30d4\u30fc\uff09\u5b58\u5728\u3057\u307e\u3059\u3002\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306eDNA\u30b3\u30d4\u30fc\u6570\uff08mtDNAcn\uff09\u306f\u3001\u7279\u306b\u5375\u5b50\u3067\u591a\u304f\u3001\u306a\u3093\u306820\u4e07\u30b3\u30d4\u30fc\u4ee5\u4e0a\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3001\u7cbe\u5b50\u3067\u306f10\u304b\u30891500\u30b3\u30d4\u30fc\u3050\u3089\u3044\u5b58\u5728\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306emtDNAcn\u3068\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2DNA\u306e\u6b20\u5931\uff08mtDNAdel\uff09\u306f\u3001\u764c\u3001\u795e\u7d4c\u7570\u5e38\u3001\u8001\u5316\u306a\u3069\u306b\u304a\u3044\u3066\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u306e\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3068\u306a\u308a\u5f97\u308b\u3053\u3068\u304c\u65e2\u306b\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3067\u306f\u3001mtDNAcn\u306f\u751f\u6b96\u5206\u91ce\u306b\u304a\u3044\u3066\u3082\u5f79\u7acb\u3066\u308b\u3053\u3068\u304c\u51fa\u6765\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n\n\n\n<p>\u4eca\u56de\u7d39\u4ecb\u3059\u308b\u8ad6\u6587\u3067\u306f\u3001\u7cbe\u5b50\u4e2d\u306emtDNAcn\u304c\u598a\u5a20\u3059\u308b\u78ba\u7387\u306b\u5f71\u97ff\u3059\u308b\u304b\u691c\u8a3c\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>Sperm mitochondrial DNA biomarkers and couple fecundity<\/p>\n\n\n\n<p>Human Reproduction, Volume 35, Issue 11, November 2020<\/p>\n\n\n\n<p>\u5bfe\u8c61\u30fb\u65b9\u6cd5<\/p>\n\n\n\n<p>2005\u5e74\u304b\u30892009\u5e74\u306b\u304b\u3051\u3066\u30a2\u30e1\u30ea\u30ab\u306e16\u306e\u7fa4\u304b\u3089\u63a1\u7528\u3055\u308c\u305f384\u7d44\u306e\u30ab\u30c3\u30d7\u30eb\u3092\u5bfe\u8c61\u3068\u3057\u305f\u3001\u4eba\u53e3\u30d9\u30fc\u30b9\u306e\u524d\u5411\u304d\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u3067\u3059\u3002\u7814\u7a76\u306b\u53c2\u52a0\u3057\u305f\u30ab\u30c3\u30d7\u30eb\u306e\u6761\u4ef6\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3057\u305f\u3002\uff081\uff09committed relationship\u3067\u3042\u308a\u3001\u598a\u5a20\u3059\u308b\u305f\u3081\u306b\u907f\u598a\u3092\u4e2d\u6b62\u3059\u308b\u3053\u3068\u3092\u8a08\u753b\u3057\u3066\u3044\u308b\u3002\uff082\uff09\u904e\u53bb1\u5e74\u9593\u306b\u6ce8\u5c04\u306b\u3088\u308b\u907f\u598a\u85ac\u3092\u4f7f\u7528\u3057\u3066\u3044\u306a\u3044\u3001\u307e\u305f\u306f2\u304b\u6708\u3092\u8d85\u3048\u3066\u907f\u598a\u3092\u884c\u3063\u3066\u3044\u306a\u3044\u3002\uff083\uff0918\u304b\u308940\u6b73\u306e\u5973\u6027\u304a\u3088\u307318\u6b73\u4ee5\u4e0a\u306e\u7537\u6027\u3002\uff084\uff09\u5973\u6027\u306e\u81ea\u5df1\u7533\u544a\u306b\u3088\u308b\u6708\u7d4c\u5468\u671f\u304c21\u65e5\u304b\u308942\u65e5\u306e\u9593\u3067\u3042\u308b\u3053\u3068\u3002\uff085\uff09\u82f1\u8a9e\u307e\u305f\u306f\u30b9\u30da\u30a4\u30f3\u8a9e\u3067\u306e\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u80fd\u529b\u3002\u904e\u53bb\u306b\u4e0d\u598a\u6cbb\u7642\u3092\u53d7\u3051\u305f\u3053\u3068\u304c\u3042\u308b\u3068\u5831\u544a\u3057\u3066\u3044\u308b\u30ab\u30c3\u30d7\u30eb\u306f\u5bfe\u8c61\u5916\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p>384\u500b\u306e\u7cbe\u6db2\u30b5\u30f3\u30d7\u30eb\u304b\u3089\u306e\u7cbe\u5b50mtDNAcn\u304a\u3088\u3073mtDNAdel\u306f\u3001\u5b9a\u91cf\u7684PCR\u306b\u3088\u3063\u3066\u8a55\u4fa1\u3055\u308c\u307e\u3057\u305f\u3002\u7cbe\u5b50mtDNAcn\u306b\u5fdc\u3058\u3066\u3001Q1\uff08mtDNAcm 0.80-2.60\uff09\u3001Q2\uff082.61-3.96\uff09\u3001Q3\uff083.98-6.38\uff09\u3001Q4\uff086.40-61.94\uff09\u306e4\u3064\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u5206\u3051\u3089\u308c\u307e\u3057\u305f\u30021\u5e74\u4ee5\u5185\u306b\u598a\u5a20\u3059\u308b\u78ba\u7387\u3092\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2DNA\u3067\u6bd4\u8f03\u3057\u3001\u96e2\u6563\u6642\u9593\u6bd4\u4f8b\u30cf\u30b6\u30fc\u30c9\u30e2\u30c7\u30eb\u3092\u7528\u3044\u3066\u3001\u5171\u5909\u91cf\u3092\u8abf\u6574\u3057\u305f\u598a\u5a20\u307e\u3067\u306e\u6642\u9593\uff08TTP\uff09\u3068\u306e\u95a2\u4fc2\u304c\u8a55\u4fa1\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u7d50\u679c<\/p>\n\n\n\n<p>\u7537\u6027\u306e\u5e73\u5747\u5e74\u9f62\u306f31.8\u2009\u00b1\u20094.8\u6b73\u3067\u3001\u5e73\u5747BMI\u306f29.9\u2009\u00b1\u20095.8\u3067\u3057\u305f\u3002\u7537\u6027\u306e\u5927\u591a\u6570\u306f\u767d\u4eba\u3067\u3057\u305f\uff08311\u4eba\u300181.0%\uff09\u3002\u5e73\u5747\u7cbe\u5b50mtDNAcn\u3068mtDNAdel\u306f\u305d\u308c\u305e\u308c5.55\u2009\u00b1\u20095.3\u30680.31\u2009\u00b1\u20090.08\u3067\u3057\u305f\u3002\u7cbe\u5b50mtDNAcn\u3068mtDNAdel\u306f\u5f37\u3044\u6b63\u306e\u76f8\u95a2\uff08P &lt; 0.001\uff09\u3092\u793a\u3057\u307e\u3057\u305f\u3002mtDNAcn\u306812\u30f6\u6708\u4ee5\u5185\u306b\u598a\u5a20\u3059\u308b\u7d2f\u7a4d\u78ba\u7387\u3068\u306e\u9593\u306b\u5f37\u3044\u8ca0\u306e\u76f8\u95a2\u304c\u89b3\u5bdf\u3055\u308c\u3001mtDNAcn\u304c\u9ad8\u3044\u307b\u3069\u598a\u5a20\u78ba\u7387\u306f\u6e1b\u5c11\u3057\u307e\u3057\u305f\uff08Q1 = 82.3%\u3001Q2 = 75.0%\u3001Q1 = 67.7%\u3001Q1 = 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