{"id":6611,"date":"2020-10-24T14:24:10","date_gmt":"2020-10-24T05:24:10","guid":{"rendered":"https:\/\/www.oakclinic-group.com\/blog\/?p=6611"},"modified":"2020-10-26T08:32:26","modified_gmt":"2020-10-25T23:32:26","slug":"%e9%a1%95%e5%be%ae%e6%8e%88%e7%b2%be%e3%81%a7%e3%81%ae%e5%ae%8c%e5%85%a8%e5%8f%97%e7%b2%be%e9%9a%9c%e5%ae%b3%e3%82%92%e6%94%b9%e5%96%84%e3%81%99%e3%82%8b%e6%b2%bb%e7%99%82","status":"publish","type":"post","link":"https:\/\/www.oakclinic-group.com\/blog\/2020\/10\/24\/%e9%a1%95%e5%be%ae%e6%8e%88%e7%b2%be%e3%81%a7%e3%81%ae%e5%ae%8c%e5%85%a8%e5%8f%97%e7%b2%be%e9%9a%9c%e5%ae%b3%e3%82%92%e6%94%b9%e5%96%84%e3%81%99%e3%82%8b%e6%b2%bb%e7%99%82\/","title":{"rendered":"\u9855\u5fae\u6388\u7cbe\u3067\u306e\u5b8c\u5168\u53d7\u7cbe\u969c\u5bb3\u3092\u6539\u5584\u3059\u308b\u6cbb\u7642"},"content":{"rendered":"\n<p>\u80da\u57f9\u990a\u58eb\u306e\u5965\u5e73\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4eca\u56de\u306f\u3001\u9855\u5fae\u6388\u7cbe\uff08ICSI\uff09\u3067\u306e\u5b8c\u5168\u53d7\u7cbe\u969c\u5bb3\u3092\u6539\u5584\u3059\u308b\u6cbb\u7642\u306b\u95a2\u3057\u3066\u65b0\u305f\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u793a\u3057\u305f\u8ad6\u6587\u3092\u7d39\u4ecb\u81f4\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>Identification and treatment of men with phospholipase C\u03b6-defective spermatozoa.<\/p>\n\n\n\n<p>Cheung S, Xie P, Parrella A, Keating D, Rosenwaks Z, Palermo GD.<\/p>\n\n\n\n<p>Fertil Steril. 2020 Sep;114(3):535-544.<\/p>\n\n\n\n<p>ICSI\u306f\u3001\u5375\u5b50\u306b1\u500b\u306e\u7cbe\u5b50\u3092\u76f4\u63a5\u6ce8\u5165\u3059\u308b\u65b9\u6cd5\u3067\u3042\u308a\u3001\u73fe\u72b6\u3067\u306f\u6700\u3082\u9ad8\u5ea6\u306a\u751f\u6b96\u88dc\u52a9\u533b\u7642\u3067\u3059\u3002\u3057\u304b\u3057\u3001ICSI\u3067\u78ba\u5b9f\u306b\u7cbe\u5b50\u3092\u5375\u5b50\u5185\u306b\u6ce8\u5165\u51fa\u6765\u3066\u3044\u3066\u3082\u3001\u5168\u304f\u53d7\u7cbe\u3057\u3066\u3044\u306a\u3044\u3001\u3082\u3057\u304f\u306f\u53d7\u7cbe\u7387\u304c\u8457\u3057\u304f\u4f4e\u3044\u3053\u3068\u304c\u3042\u308a\u3001\u3053\u308c\u3092\u5b8c\u5168\u53d7\u7cbe\u969c\u5bb3\u3068\u547c\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>ICSI\u5f8c\u306b\u53d7\u7cbe\u304c\u6210\u7acb\u3059\u308b\u70ba\u306b\u306f\u30011) 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59.0% vs. \u5bfe\u7167\u533a 2.1%\uff09\u3068\u81e8\u5e8a\u598a\u5a20\u7387\uff08\u4fee\u6b63\u533a 32.9% vs. \u5bfe\u7167\u533a 0%\uff09\u306e\u8457\u3057\u3044\u6539\u5584\u304c\u5f97\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>PLC\u03b6\u691c\u67fb\u967d\u6027\u306e\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u3001\u30de\u30a6\u30b9\u5375\u6d3b\u6027\u5316\u8a66\u9a13\u306e\u5b9f\u65bd\u3084\u3001PLC\u03b6\u304a\u3088\u3073\u7cbe\u5b50\u5f62\u6210\u7b49\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u8abf\u3079\u3001\u7cbe\u5b50\u5074\u306b\u539f\u56e0\u304c\u3042\u308b\u3053\u3068\u3092\u518d\u78ba\u8a8d\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u5f8c\u3001\u4eba\u70ba\u7684\u306a\u5375\u5b50\u6d3b\u6027\u5316\u51e6\u7406\u3092\u4f75\u7528\u3057\u305fICSI\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u53d7\u7cbe\u7387\uff08\u51e6\u7406\u533a 42.1% vs. \u5bfe\u7167\u533a 9.1%\uff09\u3068\u81e8\u5e8a\u598a\u5a20\u7387\uff08\u51e6\u7406\u533a 36.0% vs. 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