{"id":3173,"date":"2012-01-27T09:10:00","date_gmt":"2012-01-27T00:10:00","guid":{"rendered":"https:\/\/www.oakclinic-group.com\/blog\/?p=3173"},"modified":"2020-07-15T15:47:56","modified_gmt":"2020-07-15T06:47:56","slug":"kitaya-63","status":"publish","type":"post","link":"https:\/\/www.oakclinic-group.com\/blog\/2012\/01\/27\/kitaya-63\/","title":{"rendered":"\u7740\u5e8a\u4e0d\u5168\u3068\u4e0d\u80b2\u75c7"},"content":{"rendered":"\n<p>\u533b\u5c40\u30ab\u30f3\u30d5\u30a1\u30ec\u30f3\u30b9\u3067\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><img decoding=\"async\" src=\"https:\/\/www.oakclinic-group.com\/blog\/wp-content\/uploads\/2020\/03\/141217_office.jpg\" alt=\"\" class=\"wp-image-1483\" width=\"180\"\/><\/figure><\/div>\n\n\n\n<p><a href=\"https:\/\/www.oakclinic-group.com\/blog\/2012\/01\/05\/kitaya-64\/\">\u524d\u56de<\/a>\u3000(1\u67085\u65e5)\u3000\u306e\u7d9a\u7de8\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u307e\u3067\u300c\u7740\u5e8a\u4e0d\u5168\u3068\u4e0d\u80b2\u75c7\u306f\u5206\u3051\u3066\u8003\u3048\u308b\u3079\u304d\u300d\u3068\u30d6\u30ed\u30b0\u3067\u30b3\u30e1\u30f3\u30c8\u3057\u3066\u304d\u307e\u3057\u305f\u304c\u3001\u3053\u308c\u3092\u88cf\u4ed8\u3051\u308b\u8ad6\u6587\u304c\u6700\u8fd1\u3044\u304f\u3064\u304b\u51fa\u3066\u304d\u3066\u3044\u307e\u3059\u306e\u3067\u7d39\u4ecb\u3057\u307e\u3059\u3002<br>Koot YE, et al. Human Reproduction 2011;26(10):2636-41.<\/p>\n\n\n\n<p>\u598a\u5a20\u3092\u8003\u3048\u3066\u3044\u306a\u304446\u4eba103\u5468\u671f\u3092\u8ffd\u8de1\u3059\u308b\u3068\u300130\u4eba\u304c\u53cd\u5fdc\u3092\u793a\u3057\u3001\u3046\u306124\u4eba\u304c\u81e8\u5e8a\u7684\u598a\u5a20\u30016\u4eba\u304c\u6d41\u7523\u3068\u306a\u3063\u305f\u3002\u4e00\u65b9\u3001\u539f\u56e0\u4e0d\u660e\u4e0d\u598a\u75c7\u60a3\u8005\u306e\u5c3f\u4e2d\u306ehCG\u91cf\uff08\u598a\u5a20\u53cd\u5fdc\u306e\u5f37\u3055\uff09\u3092\u6bce\u65e5\u9023\u7d9a\u6e2c\u5b9a\u3057\u305f\u3068\u3053\u308d\u300160\u4eba133\u5468\u671f\u306e\u3046\u3061\u3001\u305f\u3063\u305f\uff11\u4eba\u306b\u53cd\u5fdc\u304c\u78ba\u8a8d\u3055\u308c\u3001\u81e8\u5e8a\u7684\u598a\u5a20\u304c\u7d99\u7d9a\u3055\u308c\u305f\u3002<br>\u30b1\u30df\u30ab\u30eb\u3092\u542b\u3081\u3066\u6d41\u7523\u4f8b\u306f\u3044\u306a\u304b\u3063\u305f\u3002\u3064\u307e\u308a\u306f\u8d85\u521d\u671f\u6d41\u7523\u304c\u539f\u56e0\u4e0d\u660e\u4e0d\u598a\u75c7\u306e\u60a3\u8005\u306e\u4e2d\u306b\u6f5c\u3093\u3067\u3044\u308b\u3068\u306f\u8003\u3048\u306b\u304f\u3044\u3002Salker MS, et al. Nature Medicine 2011;17(11):1509-13.<\/p>\n\n\n\n<p>\u3053\u306e\u5831\u544a\u3067\u306fSKG1\u3068\u3044\u3046\u30a4\u30aa\u30f3\u8f38\u9001\u306b\u95a2\u308f\u308b\u9175\u7d20\u306e\u5206\u6ccc\u671f\u4e2d\u671f\uff08\u7740\u5e8a\u306b\u3042\u305f\u308b\u6642\u671f\uff09\u306e\u5b50\u5bae\u5185\u819c\u306e\u767a\u73fe\u72b6\u614b\u306b\u6ce8\u76ee\u3057\u3066\u3044\u307e\u3059\u3002\u539f\u56e0\u4e0d\u660e\u4e0d\u598a\u75c7\u60a3\u8005\u306e\u5185\u819c\u3067\u306f\u3001\u51fa\u7523\u6b74\u306e\u3042\u308b\u5973\u6027\u306b\u6bd4\u3079\u308b\u3068SGK1\u306e\u767a\u73fe\u91cf\u304c\u5897\u52a0\u3002<br>\u4e00\u65b9\u3067\u3001\u7fd2\u6163\u6d41\u7523\u5973\u6027\u60a3\u8005\u306e\u5185\u819c\u3067\u306fSGK1\u306e\u767a\u73fe\u91cf\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u305f\u3068\u306e\u3053\u3068\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u6d3b\u6027\u5316\u3057\u305f\u5909\u7570\u578bSGK1\u3092\u5b50\u5bae\u7ba1\u8154\u4e0a\u76ae\u3067\u767a\u73fe\u3057\u305f\u30de\u30a6\u30b9\u306f\u7740\u5e8a\u4e0d\u5168\u3068\u306a\u3063\u305f\u306e\u306b\u5bfe\u3057\u3066\u3001 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