{"id":1943,"date":"2014-03-18T10:48:00","date_gmt":"2014-03-18T01:48:00","guid":{"rendered":"https:\/\/www.oakclinic-group.com\/blog\/?p=1943"},"modified":"2020-07-12T15:29:27","modified_gmt":"2020-07-12T06:29:27","slug":"kitaya-4","status":"publish","type":"post","link":"https:\/\/www.oakclinic-group.com\/blog\/2014\/03\/18\/kitaya-4\/","title":{"rendered":"\u6162\u6027\u5b50\u5bae\u5185\u819c\u708e\u2026\u305d\u306e14"},"content":{"rendered":"\n<div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><img decoding=\"async\" src=\"https:\/\/www.oakclinic-group.com\/blog\/wp-content\/uploads\/2020\/03\/141021_taguchi.jpg\" alt=\"\" class=\"wp-image-1570\" width=\"230\" srcset=\"https:\/\/www.oakclinic-group.com\/blog\/wp-content\/uploads\/2020\/03\/141021_taguchi.jpg 147w, https:\/\/www.oakclinic-group.com\/blog\/wp-content\/uploads\/2020\/03\/141021_taguchi-128x180.jpg 128w\" sizes=\"(max-width: 147px) 100vw, 147px\" \/><\/figure><\/div>\n\n\n\n<p>\u533b\u5c40\u30ab\u30f3\u30d5\u30a1\u30ec\u30f3\u30b9\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u524d\u56de\u306b\u7d9a\u3044\u3066\u3001\u6162\u6027\u5b50\u5bae\u5185\u819c\u708e\u95a2\u9023\u306e\u6700\u65b0\u8ad6\u6587\u3092\u7d39\u4ecb\u3057\u307e\u3059\u3002<br>\u300c\u4e0d\u598a\u75c7\u60a3\u8005\u306e\u6708\u7d4c\u8840\u3092\u7528\u3044\u3066\u6162\u6027\u5b50\u5bae\u5185\u819c\u708e\u3092\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3059\u308b\u3053\u3068\u306f\u53ef\u80fd\u304b\uff1f\u300d\u304c\u30c6\u30fc\u30de\u3067\u3059\u3002(Tortorella C et al., Fertil Steril 2014;101:242-247.)<\/p>\n\n\n\n<p>2014\u5e743\u6708\u73fe\u5728\u3001\u6162\u6027\u5b50\u5bae\u5185\u819c\u708e\u306e\u8a3a\u65ad\u3092\u78ba\u5b9a\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u5185\u819c\u306e\u75c5\u7406\u7d44\u7e54\u691c\u67fb\u304c\u5fc5\u8981\u3067\u3059\u3002\u7591\u3044\u306e\u3042\u308b\u5834\u5408\u306b\u306f\u3001\u5185\u819c\u3092\u63a1\u3063\u3066\u8abf\u3079\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u4eca\u56de\u306e\u30a4\u30bf\u30ea\u30a2\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u3088\u308b\u7814\u7a76\u3067\u306f\u3001\u6708\u7d4c\u8840\u4e2d\u306e\u708e\u75c7\u7269\u8cea\u306e\u6fc3\u5ea6\u3092\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u3067\u5185\u819c\u63a1\u53d6\u306b\u3068\u3082\u306a\u3046\u4e0d\u598a\u5973\u6027\u306e\u82e6\u75db\u3092\u6e1b\u3089\u3057\u3001\u6162\u6027\u5b50\u5bae\u5185\u819c\u708e\u306e\u8a3a\u65ad\u306b\u4ee3\u7528\u3067\u304d\u3046\u308b\u304b\u3001\u305d\u306e\u53ef\u80fd\u6027\u3092\u691c\u8a0e\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u5185\u819c\u751f\u691c\u306b\u3088\u308a\u6162\u6027\u5b50\u5bae\u5185\u819c\u708e\u306e\u8a3a\u65ad\u304c\u3059\u3067\u306b\u78ba\u5b9a\u3057\u305f64\u540d\u306e\u4e0d\u598a\u75c7\u5973\u6027\u304b\u3089\u6708\u7d4c\u8840\u3092\u56de\u53ce\u3057\u3001IL-6, IL-1beta, TNFalpha\u306e3\u3064\u306e\u708e\u75c7\u6027\u5206\u5b50\u306e\u6fc3\u5ea6\u3092\u6e2c\u5b9a\u3057\u3001\u975e\u5185\u819c\u708e\u60a3\u800528\u4eba\u3068\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u6162\u6027\u5b50\u5bae\u5185\u819c\u708e\u60a3\u8005\u3067\u306f\u3001\u3069\u306e\u5206\u5b50\u306b\u3064\u3044\u3066\u3082\u975e\u5185\u819c\u708e\u60a3\u8005\u3088\u308a\u3082\u9ad8\u3044\u3068\u3044\u3046\u7d50\u679c\u3067\u3057\u305f\u3002<br>\u7279\u306b\u6708\u7d4c\u8840IL-6\/TNFalpha\u6fc3\u5ea6\u6bd4\u306f\u3001\u7279\u7570\u5ea6\u30fb\u967d\u6027\u7684\u4e2d\u7387\uff08\u6ce81\uff09\u3068\u3082100%\u3067\u3001\u6162\u6027\u5b50\u5bae\u5185\u819c\u708e\u306e\u4e88\u6e2c\u56e0\u5b50\u3068\u3057\u3066\u5229\u7528\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7d50\u679c\u306e\u89e3\u91c8\u306b\u304b\u306a\u308a\u6ce8\u610f\u304c\u5fc5\u8981\u3068\u611f\u3058\u307e\u3057\u305f\u3002<br>\u3068\u3044\u3046\u306e\u3082\u3001\u6162\u6027\u5b50\u5bae\u5185\u819c\u708e\u304c\u5bfe\u8c61\u4e0d\u598a\u60a3\u8005\u306e\u300c56%\u300d\u306b\u8a3a\u65ad\u3055\u308c\u3066\u3044\u308b\u304b\u3089\u3067\u3059\u3002<br>\u3053\u308c\u306f\u3001\u904e\u53bb\u306e\u3044\u305a\u308c\u306e\u5831\u544a\u304b\u3089\u5927\u304d\u304f\u9038\u8131\u3057\u305f\u6570\u5b57\u3067\u3059\u3002<br>\u8aad\u307f\u76f4\u3057\u307e\u3057\u305f\u304c\u3001\u300c\u53cd\u5fa9\u7740\u5e8a\u4e0d\u5168\u300d\u60a3\u8005\u3067\u306f\u306a\u304f\u3001\u3084\u306f\u308a\u300c\u4e0d\u598a\u75c7\u300d\u60a3\u8005\u306e56%\u306b\u5f62\u8cea\u7d30\u80de\u304c\u898b\u3064\u304b\u3063\u305f\u3001\u3068\u66f8\u304b\u308c\u3066\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u691c\u51fa\u7387\u306e\u9ad8\u3055\u306f\u3001\u6162\u6027\u5b50\u5bae\u5185\u819c\u708e\u304c\u53e4\u5178\u7684\u67d3\u8272\u6cd5\u306e\u307f\u3067\u8a3a\u65ad\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u306b\u539f\u56e0\u304c\u3042\u308a\u305d\u3046\u3067\u3059\u3002<br>\u5f53\u9662\u3067\u884c\u3063\u3066\u3044\u308b\u30b9\u30bf\u30f3\u30c0\u30fc\u30c9\u306a\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u6cd5\u3067\u306f\u8abf\u3079\u3089\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u53e4\u5178\u6cd5\u306e\u307f\u3067\u306e\u6162\u6027\u5b50\u5bae\u5185\u819c\u708e\u306e\u8a3a\u65ad\u306e\u96e3\u3057\u3055\u306f\u3001\u3053\u306e\u30d6\u30ed\u30b0\u3067\u3082\u7d39\u4ecb\u3057\u3066\u304d\u305f\u3068\u304a\u308a\u3067\u3001<br>(Bayer-Garner IB et al., Arch Pathol Lab Med 2004;128:1000-1003.<br>Kitaya K et al., Diagnostic Histopathology 2013;19:231-237)<br>\u3053\u306e\u7814\u7a76\u306b\u304b\u306a\u308a\u306e\u30d0\u30a4\u30a2\u30b9\u3092\u3082\u305f\u3089\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u9759\u8108\u8840\u4e2d\u306e\u708e\u75c7\u6027\u7269\u8cea\u306e\u6fc3\u5ea6\u6e2c\u5b9a\u306f\u3001\u53e4\u304f\u304b\u3089\u65b9\u6cd5\u306f\u78ba\u7acb\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u3044\u307e\u3060\u306b\u9ad8\u984d\u3067\u3059\u3002<br>\u63a1\u8840\u3067\u306f\u306a\u304f\u6708\u7d4c\u8840\u3092\u30b5\u30f3\u30d7\u30eb\u3068\u3057\u3066\u4f7f\u3046\u3068\u306a\u308b\u3068\u3001\u305d\u306e\u7cbe\u5ea6\u7ba1\u7406\u3082\u542b\u3081\u3066\u3001\u81e8\u5e8a\u306b\u5c0e\u5165\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u306f\u672a\u77e5\u6570\u3067\u3059\u3002\u8208\u5473\u6df1\u3044\u53d6\u308a\u7d44\u307f\u3067\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u4eca\u5f8c\u3055\u3089\u306b\u8cea\u306e\u9ad8\u3044\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u304c\u5fc5\u8981\u3068\u8003\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6ce81)<br>\u7279\u7570\u5ea6\u306f\u3001\u300c\u75c5\u6c17\u306b\u7f79\u3063\u3066\u3044\u306a\u3044\u4eba\u300d\u3092\u300c\u7f79\u3063\u3066\u3044\u306a\u3044\u300d\u3068\u8a3a\u65ad\u3067\u304d\u308b\u78ba\u7387\u3092\u6307\u3057\u307e\u3059\u3002<br>\u7279\u7570\u5ea6\u304c\u4f4e\u3044\u81e8\u5e8a\u691c\u67fb\u3067\u306f\u3001\u300c\u75c5\u6c17\u3067\u306a\u3044\u4eba\u300d\u3092\u300c\u75c5\u6c17\u3067\u3042\u308b\u300d\u3068\u5224\u65ad\u3057\u3066\u3057\u307e\u3046\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002<br>\u967d\u6027\u7684\u4e2d\u7387\u306f\u3001\u300c\u691c\u67fb\u304c\u967d\u6027\u3068\u51fa\u305f\u4eba\u300d\u306e\u3046\u3061\u300c\u5b9f\u969b\u306b\u75c5\u6c17\u306b\u7f79\u3063\u3066\u3044\u308b\u4eba\u300d\u3068\u8a3a\u65ad\u3067\u304d\u308b\u78ba\u7387\u3092\u6307\u3057\u307e\u3059\u3002<br>\u6628\u5e74\u304b\u3089\u8a71\u984c\u306b\u306a\u3063\u3066\u3044\u308b\u65b0\u3057\u3044\u51fa\u751f\u524d\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306f\u3001\u967d\u6027\u7684\u4e2d\u7387\u304c\u4f4e\u3044\u3053\u3068\u304c\u554f\u984c\u306b\u306a\u3063\u3066\u3044\u307e\u3059<br>(40\u6b73\u306e\u598a\u5a66\u304c\u3053\u306e\u691c\u67fb\u3067\u30c0\u30a6\u30f3\u75c7\u5019\u7fa4\u3001\u3068\u8a3a\u65ad\u3055\u308c\u3066\u3082\u300117%\u306f\u30c0\u30a6\u30f3\u75c7\u5019\u7fa4\u3067\u306f\u306a\u3044)\u3002<br>\u3053\u306e\u3088\u3046\u306a\u691c\u67fb\u3092\u78ba\u5b9a\u8a3a\u65ad\u306e\u305f\u3081\u306b\u7528\u3044\u308b\u306e\u306f\u5371\u967a\u3068\u3044\u3048\u307e\u3059\u3002 <\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u524d\u56de\u306b\u7d9a\u3044\u3066\u3001\u6162\u6027\u5b50\u5bae\u5185\u819c\u708e\u95a2\u9023\u306e\u6700\u65b0\u8ad6\u6587\u3092\u7d39\u4ecb\u3057\u307e\u3059\u3002\u300c\u4e0d\u598a\u75c7\u60a3\u8005\u306e\u6708\u7d4c\u8840\u3092\u7528\u3044\u3066\u6162\u6027\u5b50\u5bae\u5185\u819c\u708e\u3092\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3059\u308b\u3053\u3068\u306f\u53ef\u80fd\u304b\uff1f\u300d\u2026<\/p>\n","protected":false},"author":1,"featured_media":1570,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u6162\u6027\u5b50\u5bae\u5185\u819c\u708e\u2026\u305d\u306e14 | \u533b\u7642\u6cd5\u4eba\u30aa\u30fc\u30af\u4f1a\u3000\u4e0d\u598a\u30d6\u30ed\u30b0<\/title>\n<meta name=\"robots\" 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