{"id":1756,"date":"2014-06-30T11:07:00","date_gmt":"2014-06-30T02:07:00","guid":{"rendered":"https:\/\/www.oakclinic-group.com\/blog\/?p=1756"},"modified":"2020-06-01T16:27:41","modified_gmt":"2020-06-01T07:27:41","slug":"inspection-kate-8","status":"publish","type":"post","link":"https:\/\/www.oakclinic-group.com\/blog\/2014\/06\/30\/inspection-kate-8\/","title":{"rendered":"\u80da\u79fb\u690d\u6642\u306e\u5b50\u5bae\u5185\u306e\u6db2\u4f53\u306e\u5206\u5e03\u3068\u6ce8\u5165\u3059\u308b\u6db2\u4f53\u306e\u7c98\u6027"},"content":{"rendered":"\n<div class=\"wp-block-image\"><figure class=\"alignright size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"126\" height=\"177\" src=\"https:\/\/www.oakclinic-group.com\/blog\/wp-content\/uploads\/2020\/02\/161229_hayashi.jpg\" alt=\"\" class=\"wp-image-879\"\/><\/figure><\/div>\n\n\n\n<p>\u3053\u3093\u306b\u3061\u306f\u3001\u30a4\u30ae\u30ea\u30b9\u304b\u3089\u6765\u305f\u30b1\u30a4\u30c8\u3067\u3059\u3002<br>\u73fe\u5728\u3001\u5f53\u9662\u3067\u80da\u57f9\u990a\u58eb\u3068\u3057\u3066\u50cd\u3044\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u80da\u79fb\u690d\u306b\u304a\u3044\u3066\u3001\u5b50\u5bae\u53ce\u7e2e\u3001\u30ab\u30c6\u30fc\u30c6\u30eb\u306e\u7a2e\u985e\u3001\u633f\u5165\u65b9\u6cd5\u3001\u80da\u306e\u5b50\u5bae\u5185\u79fb\u690d\u4f4d\u7f6e\u306a\u3069\u306f\u80da\u7740\u5e8a\u306b\u5927\u304d\u304f\u5f71\u97ff\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>A Glance into the uterus during in vitro simulation of embryo transfer.<br>Osnat et al. Human Reproduction Vol.19, No.3 pp 562-569., 2004.<\/p>\n\n\n\n<p>\u4e0a\u8a18\u8ad6\u6587\u306f\u5b50\u5bae\u5185\u3092\u60f3\u5b9a\u3057\u305f\u6a21\u578b\u3092\u4f7f\u3063\u3066\u3001\u80da\u79fb\u690d\u6642\u306e\u5b50\u5bae\u5185\u306e\u6db2\u4f53\u306e\u5206\u5e03\u3068\u6ce8\u5165\u3059\u308b\u6db2\u4f53\u306e\u7c98\u6027\u306b\u3064\u3044\u3066\u691c\u8a0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5f53\u9662\u3067\u306f\u3001\u79fb\u690d\u306e\u969b\u30ab\u30c6\u30fc\u30c6\u30eb\u5185\u3092\u7d04100\u00b5l\u306e\u57f9\u990a\u6db2\u3067\u6e80\u305f\u3057\u3001\u30ab\u30c6\u30fc\u30c6\u30eb\u306e\u5148\u7aef\u306f10\u00b5l\u306e\u7a7a\u6c17\u300110\u00b5l\u306e\u79fb\u690d\u80da\u3092\u542b\u3093\u3060\u57f9\u990a\u6db2\u300110\u00b5l\u306e\u7a7a\u6c17\u306e\u9806\u306b\u79fb\u690d\u80da\u3092\u30ab\u30c6\u30fc\u30c6\u30eb\u306b\u5438\u5f15\u3057\u307e\u3059\u3002<br>\u3053\u308c\u306f\u633f\u5165\u306e\u969b\u306b\u79fb\u690d\u80da\u304c\u9014\u4e2d\u3067\u3053\u307c\u308c\u3066\u3057\u307e\u308f\u306a\u3044\u3088\u3046\u306b\u7a7a\u6c17\u3067\u3075\u305f\u3092\u3059\u308b\u305f\u3081\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u8ad6\u6587\u3067\u306f\u7a7a\u6c17\u3068\u57f9\u990a\u6db2\u306e\u91cf\u3092\u5909\u3048\u308b\u3053\u3068\u3067\u3001\u57f9\u990a\u6db2\u306e\u62e1\u6563\u306e\u9055\u3044\u3092\u8a55\u4fa1\u3057\u3001\u57f9\u990a\u6db2\u6ce8\u5165\u6642\u306b\u3001\u57f9\u990a\u6db2\u3068\u3068\u3082\u306b\u524d\u5f8c\u306b\u5438\u5f15\u3057\u305f\u7a7a\u6c17\u304c\u30ab\u30c6\u30fc\u30c6\u30eb\u304b\u3089\u51fa\u3066\u304d\u305f\u969b\u306b\u304f\u3063\u3064\u3044\u3066\u4e00\u3064\u306e\u6ce1\u306b\u306a\u308a\u3001\u305d\u306e\u6ce1\u304c\u57f9\u990a\u6db2\u306e\u524d\u65b9\u3078\u306e\u62e1\u6563\u3092\u963b\u5bb3\u3057\u305f\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br>\u3055\u3089\u306b\u30ab\u30c6\u30fc\u30c6\u30eb\u5185\u3092\u7a7a\u6c17\u307e\u305f\u306f\u5f53\u9662\u3068\u540c\u69d8\u3001\u57f9\u990a\u6db2\u3067\u6e80\u305f\u3057\u305f\u5834\u5408\u3092\u6bd4\u8f03\u3057\u3001\u6db2\u4f53\u3067\u6e80\u305f\u3057\u305f\u307b\u3046\u304c\u6ce8\u5165\u6642\u306e\u6ce1\u304c\u5c0f\u3055\u304f\u57f9\u990a\u6db2\u306e\u62e1\u6563\u3092\u963b\u5bb3\u3057\u306a\u304b\u3063\u305f\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br>\u79fb\u690d\u80da\u5438\u5f15\u6642\u306e\u7a7a\u6c17\u304c\u633f\u5165\u306e\u969b\u306e\u6db2\u6f0f\u308c\u3092\u9632\u6b62\u3059\u308b\u3046\u3048\u3067\u5fc5\u8981\u3060\u3068\u3082\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br>\u3053\u308c\u306f\u5f53\u9662\u306e\u65b9\u6cd5\u306e\u6b63\u5f53\u6027\u3092\u8a3c\u660e\u3057\u3066\u304f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u591a\u304f\u306eART\u306e\u6280\u8853\u306f\u6210\u529f\u306e\u305f\u3081\u306b\u5982\u4f55\u306b\u81ea\u7136\u306a\u80ce\u5185\u74b0\u5883\u3092\u518d\u73fe\u3067\u304d\u308b\u304b\u304c\u91cd\u8981\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br>\u8ad6\u6587\u3067\u306f\u5b50\u5bae\u5185\u6db2\u306e\u7c98\u6027\u3092\u518d\u73fe\u3057\u3088\u3046\u3068\u8a66\u307f\u3066\u3044\u307e\u3059\u3002<br>\u5b50\u5bae\u5185\u6db2\u3068\u540c\u7b49\u306e\u7c98\u6027\u306e\u3042\u308b\u3082\u306e\u306b\u6db2\u4f53\u3092\u7f6e\u304d\u63db\u3048\u305f\u3068\u3053\u308d\u3001\u6ce1\u306e\u963b\u5bb3\u3092\u5927\u304d\u304f\u53d7\u3051\u308b\u3053\u3068\u306a\u304f\u6563\u5e03\u3055\u308c\u305f\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br>\u6ce8\u5165\u306f\u6bce\u56de\u540c\u69d8\u306e\u65b9\u6cd5\u3067\u884c\u308f\u308c\u307e\u3059\u304c\u3001\u5b9f\u969b\u306e\u79fb\u690d\u3067\u306f\u4ed6\u306b\u3082\u3044\u308d\u3044\u308d\u306a\u56e0\u5b50\u304c\u7740\u5e8a\u306e\u6210\u5426\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5f53\u9662\u3067\u306f\u7740\u5e8a\u7387\u306e\u4e0a\u6607\u3092\u76ee\u7684\u3068\u3057\u3066\u3001\u666e\u901a\u306e\u57f9\u990a\u6db2\u306b\u6bd4\u3079\u3066\u7c98\u6027\u304c\u9ad8\u304f\u3001\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u3092\u542b\u3080embryo glue\u3092\u5fc5\u8981\u306b\u5fdc\u3058\u3066\u4f7f\u7528\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>&#8212;&#8212;&#8212;<br>Greetings, I\u2019m Kate. I am from England and work as part of the Embryologist team. Embryo transfers (ET\u2019s) involve mechanical factors including uterine contractions, catheter type, catheter loading methods and optimal positioning of the tip with the aim of depositing the embryo as close as possible to the fundal wall to provide optimal conditions for successful implantation.<\/p>\n\n\n\n<p>A Glance into the uterus during in vitro simulation of embryo transfer.<br>Osnat et al. Human Reproduction Vol.19, No.3 pp 562-569., 2004.<\/p>\n\n\n\n<p>Two technical aspects of ET&#8217;s were evaluated using a transparent model of the uterine cavity. Firstly the transportation and distribution of liquid with air and secondly different viscosities between the transferred liquid and uterine fluid, these mock ET&#8217;s were digitally recorded and analyzed.<\/p>\n\n\n\n<p>At Oak Clinic, the catheter is loaded with 100\u00b5l of blastocyst medium, a 10\u00b5l gap of air prevent transport of the embryo into the catheter, 10\u00b5l of medium and embryo and finally 10\u00b5l of air to prevent any spillage.<br>This study evaluates different loading combinations of liquid (Saline) and air.<\/p>\n\n\n\n<p>After injection, the air came from the catheter tip, the two small volumes of air inside the catheter tube formed one larger air bubble, blocking the transfer of liquid forward and distributing it back towards the cervix.<br>When 100\u00b5l of air was replaced with 100\u00b5l of liquid, a smaller air bubble forced the liquid to the sides but closer to the fundus, this supports our protocol. Air at the end of the catheter is necessary to avoid liquid spillage upon insertion.<\/p>\n\n\n\n<p>Many ART procedures try to mimic natural mechanisms and environments that enhance success, so they try to match the viscosity of uterine fluid, assumed to be between 1500-2500 centipoise (cp) depending on the phase.<br>Replacing saline with glycerin-1880 cp, the transferred liquid spread around the bubble, liquid dispersion was limited and perhaps less likely to head towards the cervix. A constant velocity was used for all injections, but this varies in real ET\u2019s alongside other mechanical factors.<\/p>\n\n\n\n<p>We regularly use embryo glue that has a high viscosity and contains hyaluronan to increase implantation rates. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u80da\u79fb\u690d\u306b\u304a\u3044\u3066\u3001\u5b50\u5bae\u53ce\u7e2e\u3001\u30ab\u30c6\u30fc\u30c6\u30eb\u306e\u7a2e\u985e\u3001\u633f\u5165\u65b9\u6cd5\u3001\u80da\u306e\u5b50\u5bae\u5185\u79fb\u690d\u4f4d\u7f6e\u306a\u3069\u306f\u80da\u7740\u5e8a\u306b\u5927\u304d\u304f\u5f71\u97ff\u3059\u308b\u3068\u2026<\/p>\n","protected":false},"author":1,"featured_media":879,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ 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